Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00998764 · ClinicalTrials.gov registry record · Phase 3

A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients

A Phase 3 study, sponsored by Pfizer.

Terminated
Registry status
Phase 3
Development phase
494
Enrollment target

NCT00998764: Clinical Trial Phase 3 study, sponsored by Pfizer.

NCT00998764 is a Phase 3 study that was terminated before completion, run by Pfizer. The registered enrollment target is 494 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (36% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00998764, a Phase 3 study, was terminated before completion, sponsored by Pfizer.

TERMINATED
Registry status
Phase 3
Development phase
494 participants
Enrollment target

Study Summary

The purpose of this study is to assess the long-term safety and tolerability of bapineuzumab in subjects with Alzheimer Disease who participated in study 3133K1-3001(NCT00676143). Over 250 sites will participate in over 26 countries. Subjects will receive bapineuzumab. Each subject's participation will last approximately 4 years.

Primary Outcome

Safety was measured according to standard adverse event collection as described in the Adverse Event Section of the Results. Complete tables of events are provided there.

Interventions

  • DRUG Bapineuzumab 0.5 mg/kg

Trial Details

FieldValue
Enrollment Target 494 participants
Start Date 2009-12
Est. Completion 2012-11
Phase Phase 3
Pfizer

1,845 total trials

Why NCT00998764 stopped before completion

NCT00998764 is an interventional study that assigns participants to a tested intervention. The registered 494 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (36% lower).

The record links to 0 conditions, and to 1 intervention - of which Bapineuzumab 0.5 mg/kg is the first listed.

NCT00998764 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00998764 about?

NCT00998764 is a clinical study titled "A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients". The purpose of this study is to assess the long-term safety and tolerability of bapineuzumab in subjects with Alzheimer Disease who participated in study 3133K1-3001(NCT00676143). Over 250 sites will participate in over 26 countries. Subjects will receive bapineuzumab. Each subject's participation w...

What is the current status of trial NCT00998764?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 494 participants. The study started on 2009-12. Estimated completion is 2012-11.

What interventions are being tested in trial NCT00998764?

The interventions under investigation include: Bapineuzumab 0.5 mg/kg (DRUG).

Who is sponsoring clinical trial NCT00998764?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00998764's enrollment target sits among peer trials

494 779th of 2000 higher than 1,222 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03127267 · 495 participants · Phase 3

    Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

  • NCT06400472 · 495 participants · Phase 1

    A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

  • NCT05283720 · 496 participants · Phase 2

    A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

  • NCT06417775 · 496 participants · Phase 3

    Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00998764, the US trial registry maintained by the National Library of Medicine. NCT00998764 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.