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NCT00995670 · ClinicalTrials.gov registry record · NA

Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins

A NA study of Hyperglycemia, sponsored by US Department of Veterans Affairs.

Completed
Registry status
NA
Development phase
59
Enrollment target
1
Study location

NCT00995670 is a NA study of Hyperglycemia that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 59 participants, below the 877-participant average among 38 other Hyperglycemia trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00995670, a NA study of Hyperglycemia, has completed, sponsored by US Department of Veterans Affairs.

COMPLETED
Registry status
NA
Development phase
59 participants
Enrollment target
1
Study location

Study Summary

Anesthetic preconditioning (APC, a brief exposure to an anesthetic gas) has become an area of intense research interest because of its ability to protect tissue and organs from injury resulting from a cessation of blood flow and then a re-establishment of flow. The blood vessel lining plays a key role in this injury. This research will examine, in human volunteers, several important modifiers of APC in human blood vessels: high blood sugar, vitamin C, and statin drugs. Thus, the proposed studies will advance the investigators' understanding of mechanisms of this injury in humans and explore important modifiers of APC protection from injury.

Conditions Studied

Hyperglycemia

Interventions

  • DRUG Vitamin C
  • DRUG Sevoflurane
  • DRUG Simvastatin
  • DRUG 5% dextrose

Study Locations (1)

Wisconsin

  • Zablocki VA Medical Center, Milwaukee - Milwaukee

Trial Details

FieldValue
Enrollment Target 59 participants
Start Date 2010-03
Est. Completion 2013-09
Phase NA

Sponsor

US Department of Veterans Affairs

632 total trials

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What the Registry Record Tells You About NCT00995670

The ClinicalTrials.gov registry entry for NCT00995670 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 59 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 877-participant average among 38 other Hyperglycemia trials with a reported enrollment target (93% lower). The listed sponsor is US Department of Veterans Affairs, which has 632 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hyperglycemia appearing as the primary indexed condition, and to 4 interventions - of which Vitamin C is the first listed.

NCT00995670 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT00995670 about?

NCT00995670 is a clinical study titled "Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins". Anesthetic preconditioning (APC, a brief exposure to an anesthetic gas) has become an area of intense research interest because of its ability to protect tissue and organs from injury resulting from a cessation of blood flow and then a re-establishment of flow. The blood vessel lining plays a key ro...

What is the current status of trial NCT00995670?

This trial is currently completed. It is a NA study. The enrollment target is 59 participants. The study started on 2010-03. Estimated completion is 2013-09.

What conditions does trial NCT00995670 study?

This clinical trial studies the following conditions: Hyperglycemia.

What interventions are being tested in trial NCT00995670?

The interventions under investigation include: Vitamin C (DRUG), Sevoflurane (DRUG), Simvastatin (DRUG), 5% dextrose (DRUG).

Who is sponsoring clinical trial NCT00995670?

This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00995670 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.