Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00994747 · ClinicalTrials.gov registry record · NA
Sensitive Periods in Early Flavor Learning
A NA study, sponsored by Monell Chemical Senses Center.
- Completed
- Registry status
- NA
- Development phase
- 79
- Enrollment target
NCT00994747 is a NA study that has completed, run by Monell Chemical Senses Center. The registered enrollment target is 79 participants.
The verdict
NCT00994747, a NA study, has completed, sponsored by Monell Chemical Senses Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 79 participants
- Enrollment target
Study Summary
Flavor is the primary dimension by which young children determine food acceptance. However, children are not merely miniature adults since sensory systems mature postnatally and their responses to certain tastes differ markedly from adults. Moreover, emerging research has revealed that there are sensitive periods during infancy such that early flavor experiences serve to modify later responses to flavors and foods. The proposed study aims to investigate this important issue by using as a model system a class of infant formulas which are hydrolyzed protein based and thus have very pronounced and distinctive flavors which are unpalatable to older-aged infants and adults. This research was initiated because of anecdotal reports by pediatricians that although it is easy to introduce this type of formula to infants during the first months of life, it becomes extremely difficult to do so later in infancy. Indeed, recent studies in the investigators' laboratory provided the first experimental demonstration that infants younger than 4 months of age willingly accept substantial amounts of, and satiate while feeding, a novel, protein hydrolysate formula. In marked contrast, infants older than 4 months reject the protein hydrolysate formula and this rejection occurs within the first minute of a feed, a finding that strongly suggests the sensory qualities of the formula are responsible, at least in part, for this rejection. Moreover, this rejection is not evident when the investigators test older-aged infants with other unfamiliar, but non-hydrolysate, formulas. In other words, the rejection appears to be in response to a particular component or components of protein hydrolysate formulas. This shift in acceptability can be ameliorated by prior exposure. That is, if these formulas are introduced to infants within the first few months of life and are fed continuously, they remain highly acceptable throughout infancy and early childhood. These observations implicate a sensitive pe
Interventions
- OTHER Nutramigen (Flavor and Type of Infant Formula)
- OTHER Enfamil, milk-based formula
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 79 participants |
| Start Date | 2006-11 |
| Est. Completion | 2010-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00994747
The ClinicalTrials.gov registry entry for NCT00994747 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 79 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Monell Chemical Senses Center, which has 16 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Nutramigen (Flavor and Type of Infant Formula) is the first listed.
NCT00994747 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00994747 about?
NCT00994747 is a clinical study titled "Sensitive Periods in Early Flavor Learning". Flavor is the primary dimension by which young children determine food acceptance. However, children are not merely miniature adults since sensory systems mature postnatally and their responses to certain tastes differ markedly from adults. Moreover, emerging research has revealed that there are sen...
What is the current status of trial NCT00994747?
This trial is currently completed. It is a NA study. The enrollment target is 79 participants. The study started on 2006-11. Estimated completion is 2010-06.
What interventions are being tested in trial NCT00994747?
The interventions under investigation include: Nutramigen (Flavor and Type of Infant Formula) (OTHER), Enfamil, milk-based formula (OTHER).
Who is sponsoring clinical trial NCT00994747?
This trial is sponsored by Monell Chemical Senses Center, which has 16 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.