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NCT00992719 · ClinicalTrials.gov registry record · Phase 2

Novartis H1N1 Vaccine in Pregnant Women

A Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
84
Enrollment target

NCT00992719: Completed Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00992719 is a Phase 2 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 84 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (37% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00992719, a Phase 2 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
84 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety of a 2009 H1N1 influenza vaccine in pregnant women and to determine how their body reacts to different strengths of the vaccine. Two strengths of the H1N1 influenza vaccine will be tested. Since it is not known if the response to the vaccine in pregnant women is the same or different than in non-pregnant women, the study also includes a group of women who are not pregnant for comparison. Participants include 200 pregnant women and 100 non-pregnant women ages 18-39. Study procedures include physical exams, several blood samples and maintaining a memory aid to document daily temperature and side effects for 8 days following vaccination. Participants will be involved in study related procedures for about 6 months.

Primary Outcome

Participants were contacted after delivery, and medical records reviewed, to collect complications experienced during pregnancy, labor and delivery. The data collection process followed a prospectively-defined list of complications reported for this outcome measure, some of which may have also been reported as serious adverse events if otherwise meeting those requirements.

Interventions

  • BIOLOGICAL Inactivated H1N1 Vaccine

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2009-11
Est. Completion 2011-02
Phase Phase 2

What the finished NCT00992719 record still lists

NCT00992719 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (37% lower).

The record links to 0 conditions, and to 1 intervention - of which Inactivated H1N1 Vaccine is the first listed.

NCT00992719 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00992719 about?

NCT00992719 is a clinical study titled "Novartis H1N1 Vaccine in Pregnant Women". The purpose of this study is to evaluate the safety of a 2009 H1N1 influenza vaccine in pregnant women and to determine how their body reacts to different strengths of the vaccine. Two strengths of the H1N1 influenza vaccine will be tested. Since it is not known if the response to the vaccine in pre...

What is the current status of trial NCT00992719?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2009-11. Estimated completion is 2011-02.

What interventions are being tested in trial NCT00992719?

The interventions under investigation include: Inactivated H1N1 Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00992719?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00992719's enrollment target sits among peer trials

84 822nd of 2000 higher than 1,173 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00992719, the US trial registry maintained by the National Library of Medicine. NCT00992719 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.