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NCT00990275 · ClinicalTrials.gov registry record · NA
Alcohol Exposure and Airway Hyperresponsiveness
A NA study, sponsored by University of Nebraska.
- Completed
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT00990275: Completed NA study, sponsored by University of Nebraska.
NCT00990275 is a NA study that has completed, run by University of Nebraska. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00990275, a NA study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
Alcohol has consequences including increased risk for upper respiratory tract infections, pneumonia, acute respiratory distress syndrome (ARDS), and alcohol-induced asthma. The investigators have established that airways are specifically impacted by alcohol exposure because the airways are heavily exposed to the vapor phase of alcohol during drinking. These preliminary studies demonstrate that brief alcohol administration significantly attenuates airway hyperresponsiveness (AHR) in a mouse model leading to the hypothesis that alcohol exposure modifies airway hyperresponsiveness through a cAMP/NO- dependent mechanism.
Primary Outcome
A one-half concentration difference in the PC20FEV1 will be considered a statistically significant change in airway hyperresponsiveness.
Interventions
- OTHER ethanol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2009-10-01 |
| Est. Completion | 2013-01-16 |
| Phase | NA |
What the finished NCT00990275 record still lists
NCT00990275 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which ethanol is the first listed.
NCT00990275 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00990275 about?
NCT00990275 is a clinical study titled "Alcohol Exposure and Airway Hyperresponsiveness". Alcohol has consequences including increased risk for upper respiratory tract infections, pneumonia, acute respiratory distress syndrome (ARDS), and alcohol-induced asthma. The investigators have established that airways are specifically impacted by alcohol exposure because the airways are heavily e...
What is the current status of trial NCT00990275?
This trial is currently completed. It is a NA study. The enrollment target is 4 participants. The study started on 2009-10-01. Estimated completion is 2013-01-16.
What interventions are being tested in trial NCT00990275?
The interventions under investigation include: ethanol (OTHER).
Who is sponsoring clinical trial NCT00990275?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00990275's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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