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NCT00989183 · ClinicalTrials.gov registry record
Lifestyle Factors Study
A clinical trial, sponsored by University of Oklahoma.
- Completed
- Registry status
- 41
- Enrollment target
NCT00989183: Completed study, sponsored by University of Oklahoma.
NCT00989183 is a clinical trial that has completed, run by University of Oklahoma. The registered enrollment target is 41 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00989183 has completed, sponsored by University of Oklahoma.
- COMPLETED
- Registry status
- 41 participants
- Enrollment target
Study Summary
The goals of this research proposal are to further our understanding of the reproductive aging process in women and to improve our ability to clinically assess and model reproductive aging. Reproductive aging is a continuous process that begins many years prior to menopause. Women in their late 30s and early 40s usually maintain normal menstrual function and ovulatory status, yet fertility in these women is considerably compromised compared to younger women. The primary mechanism of reproductive aging is through the process of ovarian primordial follicle (egg) depletion, a process that exhibits considerable variation between women. As a result, the age at which an individual begins to experience infertility and menstrual cycle changes secondary to follicle depletion also varies significantly and is difficult to predict. Multiple studies have investigated the impact of lifestyle choices (tobacco use, oral contraceptives, BMI, alcohol use, and parity) on reproductive lifespan by correlating the impact of these exposures with the age of spontaneous menopause. Although occasionally in agreement, many of these studies report contradictory findings. Alcohol use either delays or has no effect upon the age of spontaneous menopause. Similarly, oral contraceptive pill use has been suggested to both accelerate and delay the onset of menopause. The most consistent findings regarding the impact of these factors is an acceleration in the age of menopause by 1-2 years in smokers. Given the lack of consistent findings in these investigations, the exact impact of lifestyle factors on reproductive age is currently unknown. Nevertheless, the magnitude of such exposures in the U.S. population is considerable, with 19% of adult women using oral contraceptives and 19.2% current smokers according to recent statistics. This proposal seeks to develop better models of normal female reproductive aging through anatomical studies investigating the impact of lifestyle choices on ovarian primordi
Interventions
- OTHER Women undergoing a bilateral or unilateral oophorectomy at OU Medical Center, Oklahoma City, Oklahoma
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2009-08-19 |
| Est. Completion | 2020-08-27 |
What the finished NCT00989183 record still lists
NCT00989183 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 41 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Women undergoing a bilateral or unilateral oophorectomy at OU Medical Center, Oklahoma City, Oklahoma is the first listed.
NCT00989183 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00989183 about?
NCT00989183 is a clinical study titled "Lifestyle Factors Study". The goals of this research proposal are to further our understanding of the reproductive aging process in women and to improve our ability to clinically assess and model reproductive aging. Reproductive aging is a continuous process that begins many years prior to menopause. Women in their late 30s ...
What is the current status of trial NCT00989183?
This trial is currently completed. The enrollment target is 41 participants. The study started on 2009-08-19. Estimated completion is 2020-08-27.
What interventions are being tested in trial NCT00989183?
The interventions under investigation include: Women undergoing a bilateral or unilateral oophorectomy at OU Medical Center, Oklahoma City, Oklahoma (OTHER).
Who is sponsoring clinical trial NCT00989183?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
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