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NCT00982488 · ClinicalTrials.gov registry record · Phase 2

Long-term Safety of Dasatinib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

A Phase 2 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 2
Development phase
238
Enrollment target

NCT00982488: Completed Phase 2 study, sponsored by Bristol-Myers Squibb.

NCT00982488 is a Phase 2 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 238 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (79% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00982488, a Phase 2 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 2
Development phase
238 participants
Enrollment target

Study Summary

This study assesses the long-term safety and tolerability of dasatinib administered to patients with chronic myelogenous leukemia or Philadelphia chromosome positive acute lymphoblastic leukemia and experienced clinical benefit from treatment with dasatinib or imatinib in previous protocols.

Primary Outcome

AE=any new unfavorable symptom, sign, or disease or worsening of a preexisting condition that may not have a causal relationship with treatment. SAE=a medical event that at any dose results in death, persistent or significant disability/incapacity, or drug dependency/abuse; is life-threatening, an important medical event, or a congenital anomaly/birth defect; or requires or prolongs hospitalization. Related=drug-related; having certain, probable, possible, or unknown relationship to study drug.

Interventions

  • DRUG Dasatinib
  • DRUG Imatinib

Trial Details

FieldValue
Enrollment Target 238 participants
Start Date 2007-10
Est. Completion 2014-12
Phase Phase 2
Bristol-Myers Squibb

1,025 total trials

What the finished NCT00982488 record still lists

NCT00982488 is an interventional study that assigns participants to a tested intervention. The registered 238 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (79% higher).

The record links to 0 conditions, and to 2 interventions - of which Dasatinib is the first listed.

NCT00982488 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00982488 about?

NCT00982488 is a clinical study titled "Long-term Safety of Dasatinib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia". This study assesses the long-term safety and tolerability of dasatinib administered to patients with chronic myelogenous leukemia or Philadelphia chromosome positive acute lymphoblastic leukemia and experienced clinical benefit from treatment with dasatinib or imatinib in previous protocols.

What is the current status of trial NCT00982488?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 238 participants. The study started on 2007-10. Estimated completion is 2014-12.

What interventions are being tested in trial NCT00982488?

The interventions under investigation include: Dasatinib (DRUG), Imatinib (DRUG).

Who is sponsoring clinical trial NCT00982488?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00982488's enrollment target sits among peer trials

238 255th of 2000 higher than 1,746 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00982488, the US trial registry maintained by the National Library of Medicine. NCT00982488 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.