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NCT00980395 · ClinicalTrials.gov registry record · Phase 2

Bortezomib, Cladribine, and Rituximab in Treating Patients With Advanced Mantle Cell Lymphoma or Indolent Lymphoma

A Phase 2 study, sponsored by University of Arizona.

Completed
Registry status
Phase 2
Development phase
24
Enrollment target

NCT00980395 is a Phase 2 study that has completed, run by University of Arizona. The registered enrollment target is 24 participants.

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The verdict

NCT00980395, a Phase 2 study, has completed, sponsored by University of Arizona.

COMPLETED
Registry status
Phase 2
Development phase
24 participants
Enrollment target

Study Summary

RATIONALE: Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as cladribine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Giving bortezomib together with cladribine and rituximab may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving bortezomib together with cladribine and rituximab works in treating patients with advanced mantle cell lymphoma or indolent lymphoma.

Interventions

  • DRUG rituximab
  • DRUG bortezomib
  • DRUG cladribine

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2009-07-07
Est. Completion 2018-08-14
Phase Phase 2

Sponsor

University of Arizona

349 total trials

What the Registry Record Tells You About NCT00980395

The ClinicalTrials.gov registry entry for NCT00980395 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Arizona, which has 349 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which rituximab is the first listed.

NCT00980395 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00980395 about?

NCT00980395 is a clinical study titled "Bortezomib, Cladribine, and Rituximab in Treating Patients With Advanced Mantle Cell Lymphoma or Indolent Lymphoma". RATIONALE: Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as cladribine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Monoclonal antib...

What is the current status of trial NCT00980395?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2009-07-07. Estimated completion is 2018-08-14.

What interventions are being tested in trial NCT00980395?

The interventions under investigation include: rituximab (DRUG), bortezomib (DRUG), cladribine (DRUG).

Who is sponsoring clinical trial NCT00980395?

This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.