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NCT00964886 · ClinicalTrials.gov registry record · Phase 2
Efficacy of Antidepressants in Chronic Back Pain
A Phase 2 study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- Phase 2
- Development phase
- 142
- Enrollment target
NCT00964886: Completed Phase 2 study, sponsored by VA Office of Research and Development.
NCT00964886 is a Phase 2 study that has completed, run by VA Office of Research and Development. The registered enrollment target is 142 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00964886, a Phase 2 study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 142 participants
- Enrollment target
Study Summary
This 12 week placebo controlled clinical trial tests the individual and combined effects of an antidepressant medication and cognitive behavioral therapy for chronic back pain.
Primary Outcome
The DDS is self-report measure of "current" pain intensity of chronic back pain. Participants rate pain on a 20 point scale as being greater or less intense relative to 12 adjectival descriptor words which serve as anchors (eg, greater or less than "faint," "moderate," "strong"). Scores range from 0 to 20 with higher scores indicating higher pain intensity. The analysis evaluated the 'as randomized' sample at 12 weeks after baseline or last observation carried forward, after co-varying for basel
Interventions
- BEHAVIORAL cognitive behavioral therapy
- DRUG desipramine hydrochloride
- DRUG benztropine mesylate 0.125 mg daily
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 142 participants |
| Start Date | 2010-01 |
| Est. Completion | 2015-12 |
| Phase | Phase 2 |
What the finished NCT00964886 record still lists
NCT00964886 is an interventional study that assigns participants to a tested intervention. The registered 142 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 3 interventions - of which cognitive behavioral therapy is the first listed.
NCT00964886 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00964886 about?
NCT00964886 is a clinical study titled "Efficacy of Antidepressants in Chronic Back Pain". This 12 week placebo controlled clinical trial tests the individual and combined effects of an antidepressant medication and cognitive behavioral therapy for chronic back pain.
What is the current status of trial NCT00964886?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 142 participants. The study started on 2010-01. Estimated completion is 2015-12.
What interventions are being tested in trial NCT00964886?
The interventions under investigation include: cognitive behavioral therapy (BEHAVIORAL), desipramine hydrochloride (DRUG), benztropine mesylate 0.125 mg daily (DRUG).
Who is sponsoring clinical trial NCT00964886?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00964886's enrollment target sits among peer trials
142 507th of 2000 higher than 1,491 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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