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NCT00951808 · ClinicalTrials.gov registry record · NA
Preventing Acute Chest Syndrome by Transfusion Feasibility Study
A NA study, sponsored by Carelon Research.
- Completed
- Registry status
- NA
- Development phase
- 237
- Enrollment target
NCT00951808: Completed NA study, sponsored by Carelon Research.
NCT00951808 is a NA study that has completed, run by Carelon Research. The registered enrollment target is 237 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00951808, a NA study, has completed, sponsored by Carelon Research.
- COMPLETED
- Registry status
- NA
- Development phase
- 237 participants
- Enrollment target
Study Summary
Acute chest syndrome (ACS) is similar to severe pneumonia and is a common cause of hospitalizations for people with sickle cell disease (SCD). Blood transfusions are one treatment option for ACS. High levels of an enzyme called secretory phospholipase A2 (sPLA2) may be present in people before they develop ACS. This study will determine how well sPLA2 levels can predict the onset of ACS and whether identifying high sPLA2 levels allows enough time to prevent ACS with blood transfusions. Results from this study will help to determine the feasibility of conducting a larger study that would further examine the use of sPLA2 levels and blood transfusions to prevent ACS in people with SCD.
Primary Outcome
First occurence of positive infiltrate on chest x-ray
Interventions
- BEHAVIORAL Standard care
- BIOLOGICAL Single blood transfusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 237 participants |
| Start Date | 2009-07 |
| Est. Completion | 2010-07 |
| Phase | NA |
What the finished NCT00951808 record still lists
NCT00951808 is an interventional study that assigns participants to a tested intervention. The registered 237 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which Standard care is the first listed.
NCT00951808 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00951808 about?
NCT00951808 is a clinical study titled "Preventing Acute Chest Syndrome by Transfusion Feasibility Study". Acute chest syndrome (ACS) is similar to severe pneumonia and is a common cause of hospitalizations for people with sickle cell disease (SCD). Blood transfusions are one treatment option for ACS. High levels of an enzyme called secretory phospholipase A2 (sPLA2) may be present in people before they ...
What is the current status of trial NCT00951808?
This trial is currently completed. It is a NA study. The enrollment target is 237 participants. The study started on 2009-07. Estimated completion is 2010-07.
What interventions are being tested in trial NCT00951808?
The interventions under investigation include: Standard care (BEHAVIORAL), Single blood transfusion (BIOLOGICAL).
Who is sponsoring clinical trial NCT00951808?
This trial is sponsored by Carelon Research, which has 50 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00951808's enrollment target sits among peer trials
237 461st of 2000 higher than 1,540 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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