Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00950638 · ClinicalTrials.gov registry record · Phase 1

A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration

A Phase 1 study, sponsored by Ophthotech Corporation.

Completed
Registry status
Phase 1
Development phase
47
Enrollment target

NCT00950638: Completed Phase 1 study, sponsored by Ophthotech Corporation.

NCT00950638 is a Phase 1 study that has completed, run by Ophthotech Corporation. The registered enrollment target is 47 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (22% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT00950638, a Phase 1 study, has completed, sponsored by Ophthotech Corporation.

COMPLETED
Registry status
Phase 1
Development phase
47 participants
Enrollment target

Study Summary

The objectives of this study are to evaluate the safety and tolerability of ARC1905 intravitreous injection in subjects with geographic atrophy secondary to dry age-related macular degeneration (AMD).

Interventions

  • DRUG Avacincaptad Pegol

Trial Details

FieldValue
Enrollment Target 47 participants
Start Date 2009-07-16
Est. Completion 2011-03-24
Phase Phase 1
Ophthotech Corporation

11 total trials

What the finished NCT00950638 record still lists

NCT00950638 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 47 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (22% lower).

The record links to 0 conditions, and to 1 intervention - of which Avacincaptad Pegol is the first listed.

NCT00950638 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00950638 about?

NCT00950638 is a clinical study titled "A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration". The objectives of this study are to evaluate the safety and tolerability of ARC1905 intravitreous injection in subjects with geographic atrophy secondary to dry age-related macular degeneration (AMD).

What is the current status of trial NCT00950638?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 47 participants. The study started on 2009-07-16. Estimated completion is 2011-03-24.

What interventions are being tested in trial NCT00950638?

The interventions under investigation include: Avacincaptad Pegol (DRUG).

Who is sponsoring clinical trial NCT00950638?

This trial is sponsored by Ophthotech Corporation, which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00950638's enrollment target sits among peer trials

47 1053rd of 2000 higher than 943 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03313011 · 47 participants

    The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech

  • NCT03467516 · 47 participants · Phase 2

    Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma

  • NCT03886662 · 47 participants · Phase 1

    A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)

  • NCT04013802 · 47 participants · Phase 1

    TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT00950638, the US trial registry maintained by the National Library of Medicine. NCT00950638 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.