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NCT00949182 · ClinicalTrials.gov registry record · Phase 2
Sorafenib Tosylate Before and After Hepatic Arterial Chemoembolization With Doxorubicin Hydrochloride and Mitomycin C in Treating Patients With Localized Liver Cancer That Cannot Be Removed by Surgery
A Phase 2 study of Liver Cancer, sponsored by Rutgers, The State University of New Jersey.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT00949182: Completed Phase 2 study of Liver Cancer, sponsored by Rutgers, The State University of New Jersey.
NCT00949182 is a Phase 2 study of Liver Cancer that has completed, run by Rutgers, The State University of New Jersey. The registered enrollment target is 20 participants, below the 448-participant average among 78 other Liver Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00949182, a Phase 2 study of Liver Cancer, has completed, sponsored by Rutgers, The State University of New Jersey.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
RATIONALE: Sorafenib tosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as doxorubicin hydrochloride and mitomycin C, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Chemoembolization kills tumor cells by carrying drugs directly into the tumor and blocking blood flow to the tumor. Giving sorafenib tosylate before and after chemoembolization may kill more tumor cells. PURPOSE: This phase II trial is studying the side effects and how well giving sorafenib tosylate before and after hepatic arterial chemoembolization with doxorubicin hydrochloride and mitomycin C works in treating patients with localized liver cancer that cannot be removed by surgery.
Conditions Studied
Interventions
- OTHER laboratory biomarker analysis
- DRUG sorafenib tosylate, HACE : Doxorubicin Hydrochloride and Mitomycin C
Study Locations (1)
New Jersey
- Rutgers University Hospital - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2009-07 |
| Est. Completion | 2013-06 |
| Phase | Phase 2 |
What the finished NCT00949182 record still lists
NCT00949182 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 448-participant average among 78 other Liver Cancer trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Liver Cancer appearing as the primary indexed condition, and to 2 interventions - of which laboratory biomarker analysis is the first listed.
NCT00949182 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT00949182 about?
NCT00949182 is a clinical study titled "Sorafenib Tosylate Before and After Hepatic Arterial Chemoembolization With Doxorubicin Hydrochloride and Mitomycin C in Treating Patients With Localized Liver Cancer That Cannot Be Removed by Surgery". RATIONALE: Sorafenib tosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as doxorubicin hydrochloride and mitomycin C, work in different ways to stop the growth of tumor cells, ei...
What is the current status of trial NCT00949182?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2009-07. Estimated completion is 2013-06.
What conditions does trial NCT00949182 study?
This clinical trial studies the following conditions: Liver Cancer.
What interventions are being tested in trial NCT00949182?
The interventions under investigation include: laboratory biomarker analysis (OTHER), sorafenib tosylate, HACE : Doxorubicin Hydrochloride and Mitomycin C (DRUG).
Who is sponsoring clinical trial NCT00949182?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00949182 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Liver Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00949182's enrollment target sits among peer trials
20 61st of 78 higher than 16 of 78 other Liver Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Liver Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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