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NCT00948766 · ClinicalTrials.gov registry record · Phase 4

Effects of Rivastigmine Patch on Activities of Daily Living and Cognition in Patients With Severe Dementia of the Alzheimer's Type (ACTION) (Study Protocol CENA713DUS44, NCT00948766) and a 24 Week Open-label Extension to Study CENA713DUS44

A Phase 4 study, sponsored by Novartis.

Completed
Registry status
Phase 4
Development phase
716
Enrollment target

NCT00948766 is a Phase 4 study that has completed, run by Novartis. The registered enrollment target is 716 participants.

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The verdict

NCT00948766, a Phase 4 study, has completed, sponsored by Novartis.

COMPLETED
Registry status
Phase 4
Development phase
716 participants
Enrollment target

Study Summary

The core study assessed the efficacy of a higher dose of rivastigmine 13.3 mg/24 h transdermally (15 cm\^2 patch) compared to a lower dose of the rivastigmine 4.6 mg/24 h transdermally (5 cm\^2 patch) in patients with Severe Dementia of the Alzheimer's Type in a 24-week study. The extension study obtained additional safety and efficacy data, as well as provided the higher dose rivastigmine patch to all patients who completed the core study for an additional 24 weeks.

Interventions

  • DRUG Placebo
  • DRUG Rivastigmine 4.6 mg/24 h (5 cm^2)
  • DRUG Rivastigmine 9.5 mg/24 h (10 cm^2)
  • DRUG Rivastigmine 13.3 mg/24 h (15 cm^2)

Trial Details

FieldValue
Enrollment Target 716 participants
Start Date 2009-07
Est. Completion 2012-06
Phase Phase 4

Sponsor

Novartis

265 total trials

What the Registry Record Tells You About NCT00948766

The ClinicalTrials.gov registry entry for NCT00948766 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 716 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis, which has 265 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT00948766 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00948766 about?

NCT00948766 is a clinical study titled "Effects of Rivastigmine Patch on Activities of Daily Living and Cognition in Patients With Severe Dementia of the Alzheimer's Type (ACTION) (Study Protocol CENA713DUS44, NCT00948766) and a 24 Week Open-label Extension to Study CENA713DUS44". The core study assessed the efficacy of a higher dose of rivastigmine 13.3 mg/24 h transdermally (15 cm\^2 patch) compared to a lower dose of the rivastigmine 4.6 mg/24 h transdermally (5 cm\^2 patch) in patients with Severe Dementia of the Alzheimer's Type in a 24-week study. The extension study ob...

What is the current status of trial NCT00948766?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 716 participants. The study started on 2009-07. Estimated completion is 2012-06.

What interventions are being tested in trial NCT00948766?

The interventions under investigation include: Placebo (DRUG), Rivastigmine 4.6 mg/24 h (5 cm^2) (DRUG), Rivastigmine 9.5 mg/24 h (10 cm^2) (DRUG), Rivastigmine 13.3 mg/24 h (15 cm^2) (DRUG).

Who is sponsoring clinical trial NCT00948766?

This trial is sponsored by Novartis, which has 265 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.