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NCT00946361 · ClinicalTrials.gov registry record
Impaired Insulin-like Growth Factor-1 (IGF-1) Generation Causes Protein Catabolism and Poor Growth in Children With Crohn Disease
A clinical trial, sponsored by Nationwide Children's Hospital.
- Terminated
- Registry status
- 1
- Enrollment target
NCT00946361: Clinical Trial study, sponsored by Nationwide Children's Hospital.
NCT00946361 is a clinical trial that was terminated before completion, run by Nationwide Children's Hospital. The registered enrollment target is 1 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00946361 was terminated before completion, sponsored by Nationwide Children's Hospital.
- TERMINATED
- Registry status
- 1 participants
- Enrollment target
Study Summary
The investigators will prospectively recruit 26 children with moderate - severe active Crohn disease (PCDAI \>30). Results will be compared to 26 patients in sustained remission (PCDAI \<10 and physician global assessment of remission over the previous 6 months) who are matched for age and gender. Subjects will be studied at baseline and six months. The primary study end-points will be leucine rate of appearance (a measure of protein breakdown) and IGF-1 levels. This study will test the hypothesis that children with greater disease severity will have worse longitudinal growth and protein catabolism. The investigators will also explore the secondary hypothesis that children with Crohn disease have abnormal IGF-1 generation which is linked to underlying inflammation and disease severity.
Interventions
- OTHER Examinations
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2009-07 |
| Est. Completion | 2010-05 |
Why NCT00946361 stopped before completion
NCT00946361 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 1 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Examinations is the first listed.
NCT00946361 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00946361 about?
NCT00946361 is a clinical study titled "Impaired Insulin-like Growth Factor-1 (IGF-1) Generation Causes Protein Catabolism and Poor Growth in Children With Crohn Disease". The investigators will prospectively recruit 26 children with moderate - severe active Crohn disease (PCDAI \>30). Results will be compared to 26 patients in sustained remission (PCDAI \<10 and physician global assessment of remission over the previous 6 months) who are matched for age and gender. S...
What is the current status of trial NCT00946361?
This trial is currently terminated. The enrollment target is 1 participants. The study started on 2009-07. Estimated completion is 2010-05.
What interventions are being tested in trial NCT00946361?
The interventions under investigation include: Examinations (OTHER).
Who is sponsoring clinical trial NCT00946361?
This trial is sponsored by Nationwide Children's Hospital, which has 188 total clinical trials registered on ClinicalTrials.gov.
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