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NCT00943293 · ClinicalTrials.gov registry record · Phase 1
Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies
A Phase 1 study, sponsored by University of Chicago.
- Terminated
- Registry status
- Phase 1
- Development phase
- 1
- Enrollment target
NCT00943293: Clinical Trial Phase 1 study, sponsored by University of Chicago.
NCT00943293 is a Phase 1 study that was terminated before completion, run by University of Chicago. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00943293, a Phase 1 study, was terminated before completion, sponsored by University of Chicago.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
This is a clinical research study designed to evaluate whether the administration of a vaccine to patients after transplant consisting of a minor histocompatibility antigen (mHag peptide) mixed with G-CSF (a drug intended to stimulate the immune system) can stimulate increased graft versus leukemia (GVL) responses without causing graft-versus-host disease (GVHD).
Interventions
- DRUG Fludarabine
- DRUG Melphalan
- DRUG Campath
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2003-05 |
| Est. Completion | 2012-01 |
| Phase | Phase 1 |
Why NCT00943293 stopped before completion
NCT00943293 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 3 interventions - of which Fludarabine is the first listed.
NCT00943293 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00943293 about?
NCT00943293 is a clinical study titled "Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies". This is a clinical research study designed to evaluate whether the administration of a vaccine to patients after transplant consisting of a minor histocompatibility antigen (mHag peptide) mixed with G-CSF (a drug intended to stimulate the immune system) can stimulate increased graft versus leukemia ...
What is the current status of trial NCT00943293?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2003-05. Estimated completion is 2012-01.
What interventions are being tested in trial NCT00943293?
The interventions under investigation include: Fludarabine (DRUG), Melphalan (DRUG), Campath (DRUG).
Who is sponsoring clinical trial NCT00943293?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00943293's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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