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NCT00939887 · ClinicalTrials.gov registry record · Phase 1

A Study Of Kappa Opioid Receptor Occupancy Of PF-04455242, Using PET (Positron Emission Tomography)

A Phase 1 study, sponsored by Pfizer.

Terminated
Registry status
Phase 1
Development phase
12
Enrollment target

NCT00939887: Clinical Trial Phase 1 study, sponsored by Pfizer.

NCT00939887 is a Phase 1 study that was terminated before completion, run by Pfizer. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00939887, a Phase 1 study, was terminated before completion, sponsored by Pfizer.

TERMINATED
Registry status
Phase 1
Development phase
12 participants
Enrollment target

Study Summary

This is a subject blind, investigator and sponsor open, randomized study consisting of 2 parts. Up to 15 healthy subjects will be included in the study. In the first part of the study the test retest reliability of the radiotracer \[11C\] PF 04767135 binding in man will be assessed. In the second part of this study, using \[11C\] PF 04767135, kappa opioid receptor occupancy (RO) will be assessed in up to three cohorts of subjects.

Interventions

  • DRUG PF-04455242

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2009-09
Est. Completion 2009-12
Phase Phase 1
Pfizer

1,845 total trials

Why NCT00939887 stopped before completion

NCT00939887 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 1 intervention - of which PF-04455242 is the first listed.

NCT00939887 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00939887 about?

NCT00939887 is a clinical study titled "A Study Of Kappa Opioid Receptor Occupancy Of PF-04455242, Using PET (Positron Emission Tomography)". This is a subject blind, investigator and sponsor open, randomized study consisting of 2 parts. Up to 15 healthy subjects will be included in the study. In the first part of the study the test retest reliability of the radiotracer \[11C\] PF 04767135 binding in man will be assessed. In the second pa...

What is the current status of trial NCT00939887?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2009-09. Estimated completion is 2009-12.

What interventions are being tested in trial NCT00939887?

The interventions under investigation include: PF-04455242 (DRUG).

Who is sponsoring clinical trial NCT00939887?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00939887's enrollment target sits among peer trials

12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00939887, the US trial registry maintained by the National Library of Medicine. NCT00939887 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.