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NCT00936702 · ClinicalTrials.gov registry record · Phase 2

Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary

A Phase 2 study, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 2
Development phase
46
Enrollment target

NCT00936702: Completed Phase 2 study, sponsored by Alliance for Clinical Trials in Oncology.

NCT00936702 is a Phase 2 study that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 46 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00936702, a Phase 2 study, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 2
Development phase
46 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well carboplatin given together with paclitaxel and everolimus works in treating patients with previously untreated cancer of unknown primary.

Primary Outcome

Confirmed tumor response was defined to be either a complete response (CR) or partial response (PR) noted as the objective status on 2 consecutive evaluations at least 4 weeks apart. Response was defined using Response Evaluation Criteria In Solid Tumors (RECIST) criteria: * Complete Response (CR): disappearance of all target lesions; * Partial Response (PR) 30% decrease in sum of longest diameter of target lesions;

Interventions

  • DRUG carboplatin
  • DRUG paclitaxel
  • DRUG everolimus

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2009-09
Est. Completion 2013-08
Phase Phase 2

What the finished NCT00936702 record still lists

NCT00936702 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower).

The record links to 0 conditions, and to 3 interventions - of which carboplatin is the first listed.

NCT00936702 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00936702 about?

NCT00936702 is a clinical study titled "Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary". RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and...

What is the current status of trial NCT00936702?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 2009-09. Estimated completion is 2013-08.

What interventions are being tested in trial NCT00936702?

The interventions under investigation include: carboplatin (DRUG), paclitaxel (DRUG), everolimus (DRUG).

Who is sponsoring clinical trial NCT00936702?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00936702's enrollment target sits among peer trials

46 1286th of 2000 higher than 705 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00936702, the US trial registry maintained by the National Library of Medicine. NCT00936702 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.