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NCT00925990 · ClinicalTrials.gov registry record · Phase 2

CTS-1027 in Interferon-Naive Hepatitis C Patients

A Phase 2 study, sponsored by Conatus Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
70
Enrollment target

NCT00925990: Completed Phase 2 study, sponsored by Conatus Pharmaceuticals.

NCT00925990 is a Phase 2 study that has completed, run by Conatus Pharmaceuticals. The registered enrollment target is 70 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00925990, a Phase 2 study, has completed, sponsored by Conatus Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
70 participants
Enrollment target

Study Summary

The study is intended to determine whether CTS-1027 either alone or in combination with ribavirin is safe and effective in Hepatitis C patients who have not previously been treated with interferon.

Primary Outcome

Measure the mean absolute changes in HCV-RNA (Hepatitis C virus ribonucleic acid, also known as "viral load") levels in the blood from before treatment (baseline) through 24 weeks of treatment. Mean Absolute Change in HCV-RNA (log) = log10(HCV-RNA Week 24) - log10(HCV-RNA Baseline)

Interventions

  • DRUG ribavirin
  • DRUG CTS-1027
  • DRUG Placebo for ribavirin

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2009-06
Est. Completion 2010-07
Phase Phase 2
Conatus Pharmaceuticals

16 total trials

What the finished NCT00925990 record still lists

NCT00925990 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% lower).

The record links to 0 conditions, and to 3 interventions - of which ribavirin is the first listed.

NCT00925990 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00925990 about?

NCT00925990 is a clinical study titled "CTS-1027 in Interferon-Naive Hepatitis C Patients". The study is intended to determine whether CTS-1027 either alone or in combination with ribavirin is safe and effective in Hepatitis C patients who have not previously been treated with interferon.

What is the current status of trial NCT00925990?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2009-06. Estimated completion is 2010-07.

What interventions are being tested in trial NCT00925990?

The interventions under investigation include: ribavirin (DRUG), CTS-1027 (DRUG), Placebo for ribavirin (DRUG).

Who is sponsoring clinical trial NCT00925990?

This trial is sponsored by Conatus Pharmaceuticals, which has 16 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00925990's enrollment target sits among peer trials

70 937th of 2000 higher than 1,036 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00925990, the US trial registry maintained by the National Library of Medicine. NCT00925990 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.