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NCT00925600 · ClinicalTrials.gov registry record · Phase 3
Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss
A Phase 3 study, sponsored by Amgen.
- Completed
- Registry status
- Phase 3
- Development phase
- 769
- Enrollment target
NCT00925600: Completed Phase 3 study, sponsored by Amgen.
NCT00925600 is a Phase 3 study that has completed, run by Amgen. The registered enrollment target is 769 participants, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00925600, a Phase 3 study, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 769 participants
- Enrollment target
Study Summary
This is a phase 3, randomized, double-blind, placebo-controlled study to evaluate new or worsening lens opacifications in men with non-metastatic prostate cancer receiving denosumab for bone loss due to androgen deprivation therapy.
Primary Outcome
The Lens Opacities Classification System III (LOCS III) is a slit lamp based opacification grading method. Photographs of slit lamp cross-sections of the lens are used as references for grading nuclear opalescence (NO) and nuclear color (NC), and photographs of the lens seen by retroillumination are used as references for grading cortical (C) and posterior subcapsular (P) cataract. Opacification severity is graded on a decimal scale, scores can range from 0.1 to 6.9 for NO and NC and from 0.1 to
Interventions
- BIOLOGICAL Placebo
- BIOLOGICAL Denosumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 769 participants |
| Start Date | 2009-11-30 |
| Est. Completion | 2016-05-12 |
| Phase | Phase 3 |
What the finished NCT00925600 record still lists
NCT00925600 is an interventional study that assigns participants to a tested intervention. The registered 769 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00925600 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00925600 about?
NCT00925600 is a clinical study titled "Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss". This is a phase 3, randomized, double-blind, placebo-controlled study to evaluate new or worsening lens opacifications in men with non-metastatic prostate cancer receiving denosumab for bone loss due to androgen deprivation therapy.
What is the current status of trial NCT00925600?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 769 participants. The study started on 2009-11-30. Estimated completion is 2016-05-12.
What interventions are being tested in trial NCT00925600?
The interventions under investigation include: Placebo (BIOLOGICAL), Denosumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT00925600?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00925600's enrollment target sits among peer trials
769 444th of 2000 higher than 1,556 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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