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NCT00920764 · ClinicalTrials.gov registry record · Phase 2

A Study of Atrasentan on Reducing Albuminuria in Type 2 Diabetic Nephropathy Treated With Renin-Angiotensin System Inhibitors

A Phase 2 study, sponsored by AbbVie (prior sponsor, Abbott).

Completed
Registry status
Phase 2
Development phase
92
Enrollment target

NCT00920764: Completed Phase 2 study, sponsored by AbbVie (prior sponsor, Abbott).

NCT00920764 is a Phase 2 study that has completed, run by AbbVie (prior sponsor, Abbott). The registered enrollment target is 92 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (31% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00920764, a Phase 2 study, has completed, sponsored by AbbVie (prior sponsor, Abbott).

COMPLETED
Registry status
Phase 2
Development phase
92 participants
Enrollment target

Study Summary

The study objective is to investigate the effects of three low doses of atrasentan on urinary albumin/creatinine ratio (UACR) levels in subjects with Type 2 diabetic nephropathy. Patients with Type 2 diabetes with nephropathy must be receiving a renin-angiotensin system inhibitor, such as an Angiotensin converting enzyme inhibitor (ACEi) or an Angiotensin II Receptor Blocker (ARB) for participation in this study. ACEi and ARB treatment are the standard of care for the management of proteinuria in Chronic Kidney Disease (CKD) patients.

Interventions

  • DRUG Placebo for Atrasentan 0.2 mg/mL solution
  • DRUG 0.25 mg Atrasentan QD
  • DRUG 0.75 mg Atrasentan QD
  • DRUG 1.75 mg Atrasentan QD

Trial Details

FieldValue
Enrollment Target 92 participants
Start Date 2009-06
Est. Completion 2010-05
Phase Phase 2
AbbVie (prior sponsor, Abbott)

88 total trials

What the finished NCT00920764 record still lists

NCT00920764 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 92 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (31% lower).

The record links to 0 conditions, and to 4 interventions - of which Placebo for Atrasentan 0.2 mg/mL solution is the first listed.

NCT00920764 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00920764 about?

NCT00920764 is a clinical study titled "A Study of Atrasentan on Reducing Albuminuria in Type 2 Diabetic Nephropathy Treated With Renin-Angiotensin System Inhibitors". The study objective is to investigate the effects of three low doses of atrasentan on urinary albumin/creatinine ratio (UACR) levels in subjects with Type 2 diabetic nephropathy. Patients with Type 2 diabetes with nephropathy must be receiving a renin-angiotensin system inhibitor, such as an Angiot...

What is the current status of trial NCT00920764?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 92 participants. The study started on 2009-06. Estimated completion is 2010-05.

What interventions are being tested in trial NCT00920764?

The interventions under investigation include: Placebo for Atrasentan 0.2 mg/mL solution (DRUG), 0.25 mg Atrasentan QD (DRUG), 0.75 mg Atrasentan QD (DRUG), 1.75 mg Atrasentan QD (DRUG).

Who is sponsoring clinical trial NCT00920764?

This trial is sponsored by AbbVie (prior sponsor, Abbott), which has 88 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00920764's enrollment target sits among peer trials

92 767th of 2000 higher than 1,230 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00920764, the US trial registry maintained by the National Library of Medicine. NCT00920764 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.