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NCT00915200 · ClinicalTrials.gov registry record · Phase 2
N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy
A Phase 2 study, sponsored by The University of Texas Health Science Center at San Antonio.
- Completed
- Registry status
- Phase 2
- Development phase
- 114
- Enrollment target
NCT00915200: Completed Phase 2 study, sponsored by The University of Texas Health Science Center at San Antonio.
NCT00915200 is a Phase 2 study that has completed, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 114 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (14% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00915200, a Phase 2 study, has completed, sponsored by The University of Texas Health Science Center at San Antonio.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 114 participants
- Enrollment target
Study Summary
The study is designed to test if the combination of two potent antioxidant nutritional supplements, N-acetylcysteine and the milk thistle extract silibin, is capable of correcting the shedding of urine protein, the oxidative stress, and the inflammation in patients with type 2 diabetes mellitus and diabetic kidney disease.
Interventions
- DIETARY_SUPPLEMENT N-acetylcysteine
- DIETARY_SUPPLEMENT silibin
- DIETARY_SUPPLEMENT high-dose silibin
- DIETARY_SUPPLEMENT N-acetylcysteine placebo
- DIETARY_SUPPLEMENT silibin placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 114 participants |
| Start Date | 2009-10 |
| Est. Completion | 2016-04 |
| Phase | Phase 2 |
What the finished NCT00915200 record still lists
NCT00915200 is an interventional study that assigns participants to a tested intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (14% lower).
The record links to 0 conditions, and to 5 interventions - of which N-acetylcysteine is the first listed.
NCT00915200 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00915200 about?
NCT00915200 is a clinical study titled "N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy". The study is designed to test if the combination of two potent antioxidant nutritional supplements, N-acetylcysteine and the milk thistle extract silibin, is capable of correcting the shedding of urine protein, the oxidative stress, and the inflammation in patients with type 2 diabetes mellitus and ...
What is the current status of trial NCT00915200?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 114 participants. The study started on 2009-10. Estimated completion is 2016-04.
What interventions are being tested in trial NCT00915200?
The interventions under investigation include: N-acetylcysteine (DIETARY_SUPPLEMENT), silibin (DIETARY_SUPPLEMENT), high-dose silibin (DIETARY_SUPPLEMENT), N-acetylcysteine placebo (DIETARY_SUPPLEMENT), silibin placebo (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00915200?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00915200's enrollment target sits among peer trials
114 627th of 2000 higher than 1,370 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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