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NCT00910988 · ClinicalTrials.gov registry record · NA
Healthy Volunteers Study of the Effects of Olanzapine and Ziprasidone
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 46
- Enrollment target
NCT00910988 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 46 participants.
The verdict
NCT00910988, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 46 participants
- Enrollment target
Study Summary
Primary Aim: To test the acute effects of olanzapine or ziprasidone administration, in comparison to placebo, on insulin sensitivity in antipsychotic-naïve healthy young men, measured as whole-body dextrose infusion rates (mg/kg/min), hepatic glucose production (glucose rate of appearance \[Ra\]), primarily muscle glucose utilization (glucose rate of disappearance \[Rd\]), and adipose tissue related free fatty acid production (glycerol rate of appearance \[Ra\]). We hypothesize that olanzapine, but not ziprasidone, will result in acute decreases in insulin sensitivity. Secondary Aim: To test the acute effects of olanzapine or ziprasidone on insulin signaling pathways in antipsychotic naïve healthy young men. We hypothesize that olanzapine, but not ziprasidone, will result in acute alterations in insulin signaling.
Interventions
- DRUG Olanzapine
- DRUG Ziprasidone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2009-02 |
| Est. Completion | 2012-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00910988
The ClinicalTrials.gov registry entry for NCT00910988 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 46 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Olanzapine is the first listed.
NCT00910988 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00910988 about?
NCT00910988 is a clinical study titled "Healthy Volunteers Study of the Effects of Olanzapine and Ziprasidone". Primary Aim: To test the acute effects of olanzapine or ziprasidone administration, in comparison to placebo, on insulin sensitivity in antipsychotic-naïve healthy young men, measured as whole-body dextrose infusion rates (mg/kg/min), hepatic glucose production (glucose rate of appearance \[Ra\]), p...
What is the current status of trial NCT00910988?
This trial is currently completed. It is a NA study. The enrollment target is 46 participants. The study started on 2009-02. Estimated completion is 2012-06.
What interventions are being tested in trial NCT00910988?
The interventions under investigation include: Olanzapine (DRUG), Ziprasidone (DRUG).
Who is sponsoring clinical trial NCT00910988?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
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