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NCT00905762 · ClinicalTrials.gov registry record · Phase 1

Concentration of Besifloxacin, Gatifloxacin, and Moxifloxacin in Human Conjunctiva After Topical Instillation

A Phase 1 study, sponsored by Bausch & Lomb Incorporated.

Completed
Registry status
Phase 1
Development phase
119
Enrollment target

NCT00905762: Completed Phase 1 study, sponsored by Bausch & Lomb Incorporated.

NCT00905762 is a Phase 1 study that has completed, run by Bausch & Lomb Incorporated. The registered enrollment target is 119 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00905762, a Phase 1 study, has completed, sponsored by Bausch & Lomb Incorporated.

COMPLETED
Registry status
Phase 1
Development phase
119 participants
Enrollment target

Study Summary

The purpose of this study is to assess the concentration of besifloxacin compared to gatifloxacin and moxifloxacin in human conjunctival tissue, following a single drop of the drug instilled topically into the study eye. Conjunctival biopsies will be performed at specified time points, followed by the use of loteprednol etabonate/tobramycin ophthalmic suspension four times a day for 5 days.

Interventions

  • DRUG Moxifloxacin
  • DRUG Gatifloxacin
  • DRUG Besifloxacin

Trial Details

FieldValue
Enrollment Target 119 participants
Start Date 2009-03
Est. Completion 2009-04
Phase Phase 1
Bausch & Lomb Incorporated

174 total trials

What the finished NCT00905762 record still lists

NCT00905762 is an interventional study that assigns participants to a tested intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% higher).

The record links to 0 conditions, and to 3 interventions - of which Moxifloxacin is the first listed.

NCT00905762 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00905762 about?

NCT00905762 is a clinical study titled "Concentration of Besifloxacin, Gatifloxacin, and Moxifloxacin in Human Conjunctiva After Topical Instillation". The purpose of this study is to assess the concentration of besifloxacin compared to gatifloxacin and moxifloxacin in human conjunctival tissue, following a single drop of the drug instilled topically into the study eye. Conjunctival biopsies will be performed at specified time points, followed by t...

What is the current status of trial NCT00905762?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 119 participants. The study started on 2009-03. Estimated completion is 2009-04.

What interventions are being tested in trial NCT00905762?

The interventions under investigation include: Moxifloxacin (DRUG), Gatifloxacin (DRUG), Besifloxacin (DRUG).

Who is sponsoring clinical trial NCT00905762?

This trial is sponsored by Bausch & Lomb Incorporated, which has 174 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00905762's enrollment target sits among peer trials

119 498th of 2000 higher than 1,502 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00905762, the US trial registry maintained by the National Library of Medicine. NCT00905762 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.