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Dyspnea clinical trials
Every US clinical trial registered for Dyspnea — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
24 US clinical trials · 7 currently recruiting
The research picture
Dyspnea has 24 registered US clinical trials, 7 of them open to new participants right now — about 29% of the total.
- 7
- recruiting participants now
- 29%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 2
- top sponsor: M.D. Anderson Cancer Center
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology
M.D. Anderson Cancer Center
NCT06336642
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
VA Office of Research and Development
NCT05937854
129Xe MRI Cardiopulmonary
Bastiaan Driehuys
NCT06038630
Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy
Ohio State University Comprehensive Cancer Center
NCT07386444
Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea
University of Rochester
NCT06554353
Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection
Tufts Medical Center
NCT05866952
The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)
University of Nebraska
NCT06524856
Improving Diagnostic Accuracy for Acute Heart Failure
Vanderbilt University Medical Center
NCT04886128
Dexamethasone in Controlling Dyspnea in Patients With Cancer
M.D. Anderson Cancer Center
NCT03367156
Breathlessness Relieved by Employing Medical Air to be Titrated by Hospitalized Patients to Improve Inpatient Experience
Ohio State University
NCT05416437
Improving Patient Prioritization During Hospital-homecare Transition
Columbia University
NCT04136951
Evaluation of Cardiopulmonary Diseases by Ultrasound
Echosense
NCT02248831
Emergency Department Cardiac Ultrasound
Hennepin Healthcare Research Institute
NCT02719509
Impact of Validated Diagnostic Prediction Model of Acute Heart Failure in the Emergency Department
Unity Health Toronto
NCT01193998
BRIPPED Scan for Evaluation of Emergency Department (ED) Patients With Shortness of Breath
Eastern Virginia Medical School
NCT01662843
Utility of Lung Clearance Index Score as a Noninvasive Marker of Deployment Lung Disease
National Jewish Health
NCT03012958
Precision of IMED-4 Lung Fluid Measurements
Intersection Medical
NCT02187770
Improving Management of Breathlessness in Patients With Lung Cancer
Massachusetts General Hospital
NCT01937637
Improving Care of Patients With Heart Failure
University of California, San Francis
NCT01461681
Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Cannulae Designs
Vapotherm
NCT04512781
Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia
US Department of Veterans Affairs
NCT00904436
Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest
Johns Hopkins University
NCT04170062
Device-guided Breathing for Shortness of Breath in COPD
Mayo Clinic
NCT01286181
Virtual Reality at End-of-life
State University of New York at Buffalo
NCT06149429
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dyspnea Trial Landscape
ClinicalTrials.gov lists 24 US studies indexed under Dyspnea, and 7 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Dyspnea shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Dyspnea is led by M.D. Anderson Cancer Center with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 24 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dyspnea?
PlainTrial tracks 24 US clinical trials for Dyspnea, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dyspnea?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.