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ClinicalTrials.gov 7 recruiting now official registry

Dyspnea clinical trials

Every US clinical trial registered for Dyspnea — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

24 US clinical trials · 7 currently recruiting

The research picture

Dyspnea has 24 registered US clinical trials, 7 of them open to new participants right now — about 29% of the total.

7
recruiting participants now
29%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: M.D. Anderson Cancer Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 2 150 participants

Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology

M.D. Anderson Cancer Center

NCT06336642

RECRUITING Phase 2 126 participants

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

VA Office of Research and Development

NCT05937854

RECRUITING Phase 2 125 participants

129Xe MRI Cardiopulmonary

Bastiaan Driehuys

NCT06038630

RECRUITING NA 58 participants

Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy

Ohio State University Comprehensive Cancer Center

NCT07386444

RECRUITING 50 participants

Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea

University of Rochester

NCT06554353

RECRUITING 40 participants

Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection

Tufts Medical Center

NCT05866952

RECRUITING NA 20 participants

The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)

University of Nebraska

NCT06524856

ACTIVE NOT RECRUITING 2,800 participants

Improving Diagnostic Accuracy for Acute Heart Failure

Vanderbilt University Medical Center

NCT04886128

ACTIVE NOT RECRUITING Phase 2 135 participants

Dexamethasone in Controlling Dyspnea in Patients With Cancer

M.D. Anderson Cancer Center

NCT03367156

ACTIVE NOT RECRUITING NA 80 participants

Breathlessness Relieved by Employing Medical Air to be Titrated by Hospitalized Patients to Improve Inpatient Experience

Ohio State University

NCT05416437

COMPLETED NA 1,915 participants

Improving Patient Prioritization During Hospital-homecare Transition

Columbia University

NCT04136951

COMPLETED NA 600 participants

Evaluation of Cardiopulmonary Diseases by Ultrasound

Echosense

NCT02248831

COMPLETED 380 participants

Emergency Department Cardiac Ultrasound

Hennepin Healthcare Research Institute

NCT02719509

COMPLETED NA 186 participants

Impact of Validated Diagnostic Prediction Model of Acute Heart Failure in the Emergency Department

Unity Health Toronto

NCT01193998

COMPLETED 104 participants

BRIPPED Scan for Evaluation of Emergency Department (ED) Patients With Shortness of Breath

Eastern Virginia Medical School

NCT01662843

COMPLETED 73 participants

Utility of Lung Clearance Index Score as a Noninvasive Marker of Deployment Lung Disease

National Jewish Health

NCT03012958

COMPLETED 46 participants

Precision of IMED-4 Lung Fluid Measurements

Intersection Medical

NCT02187770

COMPLETED NA 32 participants

Improving Management of Breathlessness in Patients With Lung Cancer

Massachusetts General Hospital

NCT01937637

COMPLETED NA 30 participants

Improving Care of Patients With Heart Failure

University of California, San Francis

NCT01461681

COMPLETED NA 26 participants

Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Cannulae Designs

Vapotherm

NCT04512781

COMPLETED NA 20 participants

Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia

US Department of Veterans Affairs

NCT00904436

COMPLETED NA 11 participants

Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest

Johns Hopkins University

NCT04170062

COMPLETED NA 11 participants

Device-guided Breathing for Shortness of Breath in COPD

Mayo Clinic

NCT01286181

COMPLETED NA 9 participants

Virtual Reality at End-of-life

State University of New York at Buffalo

NCT06149429

Phase Distribution

PhaseTrial count
Phase 2 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Dyspnea Trial Landscape

ClinicalTrials.gov lists 24 US studies indexed under Dyspnea, and 7 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Dyspnea shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Dyspnea is led by M.D. Anderson Cancer Center with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 24 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Dyspnea?

PlainTrial tracks 24 US clinical trials for Dyspnea, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Dyspnea?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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