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ClinicalTrials.gov 7 recruiting now early-phase tilt

Dyspnea: early-phase trial registry

7 of 24 indexed Dyspnea trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #686 of 28,707 conditions by registered trial count.

24 US clinical trials · 7 currently recruiting · #686 of 28,707 conditions by registered trial count

Dyspnea: 24 US clinical trials tracked, 7 recruiting.

Dyspnea is the subject of 24 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 2 of these trials.

Enrollment posture brief

Registry condition dyspnea

OPEN 7 | RECR 29% | LATE 0 | EARLY 4 | RANK #686 | SPON 2

Nearest open-share peer: Bleeding (29% recruiting · 24 trials)

Aplastic Anemia37.5%Behavior37.5%Dyspnea (this)29%Allergic Rhinitis8.3%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Dyspnea

Dyspnea lists 7 open slots (29% of 24 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Dyspnea on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Dyspnea is recruiting below its size-band peers.

    7 of 24 indexed trials (29.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Dyspnea trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 2 of 24 trials (8.3%). 23 distinct sponsors appear on at least one study for this condition label.

  3. Typical Dyspnea enrolment sits around 73 participants.

    Median target enrolment is 73 among the 24 trials that report a genuine target (sentinel values excluded). 14 of those (58.3%) plan for fewer than 100 participants.

  4. Dyspnea research is mostly interventional.

    17 interventional and 7 observational studies make up this index (70.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 24

Open and recent trials

24 total, page 1 of 1

RECRUITING Phase 2 150 participants

Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology

M.D. Anderson Cancer Center

NCT06336642

RECRUITING Phase 2 126 participants

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

VA Office of Research and Development

NCT05937854

RECRUITING Phase 2 125 participants

129Xe MRI Cardiopulmonary

Bastiaan Driehuys

NCT06038630

RECRUITING NA 58 participants

Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy

Ohio State University Comprehensive Cancer Center

NCT07386444

RECRUITING 50 participants

Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea

University of Rochester

NCT06554353

RECRUITING 40 participants

Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection

Tufts Medical Center

NCT05866952

RECRUITING NA 20 participants

The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)

University of Nebraska

NCT06524856

ACTIVE NOT RECRUITING 2,800 participants

Improving Diagnostic Accuracy for Acute Heart Failure

Vanderbilt University Medical Center

NCT04886128

ACTIVE NOT RECRUITING Phase 2 135 participants

Dexamethasone in Controlling Dyspnea in Patients With Cancer

M.D. Anderson Cancer Center

NCT03367156

ACTIVE NOT RECRUITING NA 80 participants

Breathlessness Relieved by Employing Medical Air to be Titrated by Hospitalized Patients to Improve Inpatient Experience

Ohio State University

NCT05416437

COMPLETED NA 1,915 participants

Improving Patient Prioritization During Hospital-homecare Transition

Columbia University

NCT04136951

COMPLETED NA 600 participants

Evaluation of Cardiopulmonary Diseases by Ultrasound

Echosense

NCT02248831

COMPLETED 380 participants

Emergency Department Cardiac Ultrasound

Hennepin Healthcare Research Institute

NCT02719509

COMPLETED NA 186 participants

Impact of Validated Diagnostic Prediction Model of Acute Heart Failure in the Emergency Department

Unity Health Toronto

NCT01193998

COMPLETED 104 participants

BRIPPED Scan for Evaluation of Emergency Department (ED) Patients With Shortness of Breath

Eastern Virginia Medical School

NCT01662843

COMPLETED 73 participants

Utility of Lung Clearance Index Score as a Noninvasive Marker of Deployment Lung Disease

National Jewish Health

NCT03012958

COMPLETED 46 participants

Precision of IMED-4 Lung Fluid Measurements

Intersection Medical

NCT02187770

COMPLETED NA 32 participants

Improving Management of Breathlessness in Patients With Lung Cancer

Massachusetts General Hospital

NCT01937637

COMPLETED NA 30 participants

Improving Care of Patients With Heart Failure

University of California, San Francisco

NCT01461681

COMPLETED NA 26 participants

Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Cannulae Designs

Vapotherm

NCT04512781

COMPLETED NA 20 participants

Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia

US Department of Veterans Affairs

NCT00904436

COMPLETED NA 11 participants

Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest

Johns Hopkins University

NCT04170062

COMPLETED NA 11 participants

Device-guided Breathing for Shortness of Breath in COPD

Mayo Clinic

NCT01286181

COMPLETED NA 9 participants

Virtual Reality at End-of-life

State University of New York at Buffalo

NCT06149429

Phase Distribution

PhaseTrial count
Phase 2 4

Named interventions

Most-linked intervention names on Dyspnea records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Personalized virtual reality experience Behavioral
1 trials
PREVENT clinical decision support Other
1 trials
Recording Doppler ultrasound signals noninvasively Device
1 trials
Twice daily practice of device-guided slow breathing. Behavioral
1 trials
Lung clearance index (LCI) Other
1 trials
Control Cannula - Unicorn Cannula - Prosoft Cannula Device
1 trials
Control Cannula - Prosoft Cannula - Unicorn Cannula Device
1 trials
Treatment as per usual care Other
1 trials

US sites by state

Facility locations filed on Dyspnea trials. A trial with sites in several states counts in each.

Massachusetts 5 trials
New York 4 trials
Ohio 3 trials
Texas 2 trials
Tennessee 2 trials
Nebraska 2 trials
Minnesota 2 trials
Michigan 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Dyspnea page

24 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Dyspnea condition card totals 24 registered trials; most-linked intervention Personalized virtual reality experience; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.