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NCT00893581 · ClinicalTrials.gov registry record · NA
Multimodal Neuroimaging of Treatment Effects in Adolescent Mania
A NA study, sponsored by University of Cincinnati.
- Completed
- Registry status
- NA
- Development phase
- 169
- Enrollment target
NCT00893581: Completed NA study, sponsored by University of Cincinnati.
NCT00893581 is a NA study that has completed, run by University of Cincinnati. The registered enrollment target is 169 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00893581, a NA study, has completed, sponsored by University of Cincinnati.
- COMPLETED
- Registry status
- NA
- Development phase
- 169 participants
- Enrollment target
Study Summary
Specific Aim 1: To determine the effects of treatment with quetiapine or lithium on brain activation in adolescents. The investigators will use functional magnetic resonance imaging (fMRI) to examine brain activation during an attentional task. Specific Aim 2: To determine the effects of treatment with quetiapine or lithium on neurometabolite measures, early in their illness course. The investigators will use 1H-MRS to identify myo-inositol (mI), N-acetyl aspartate (NAA), and glutamate (Glu) levels in prefrontal ALN regions. Specific Aim 3: To determine the relationships among the changes in brain activation and neurometabolite measures, as well as symptomatic improvement in manic adolescents.
Interventions
- OTHER Healthy Controls
- DRUG Quetiapine & Placebo
- DRUG Lithium and Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 169 participants |
| Start Date | 2009-03 |
| Est. Completion | 2016-03 |
| Phase | NA |
What the finished NCT00893581 record still lists
NCT00893581 is an interventional study that assigns participants to a tested intervention. The registered 169 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 3 interventions - of which Healthy Controls is the first listed.
NCT00893581 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00893581 about?
NCT00893581 is a clinical study titled "Multimodal Neuroimaging of Treatment Effects in Adolescent Mania". Specific Aim 1: To determine the effects of treatment with quetiapine or lithium on brain activation in adolescents. The investigators will use functional magnetic resonance imaging (fMRI) to examine brain activation during an attentional task. Specific Aim 2: To determine the effects of treatment ...
What is the current status of trial NCT00893581?
This trial is currently completed. It is a NA study. The enrollment target is 169 participants. The study started on 2009-03. Estimated completion is 2016-03.
What interventions are being tested in trial NCT00893581?
The interventions under investigation include: Healthy Controls (OTHER), Quetiapine & Placebo (DRUG), Lithium and Placebo (DRUG).
Who is sponsoring clinical trial NCT00893581?
This trial is sponsored by University of Cincinnati, which has 245 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00893581's enrollment target sits among peer trials
169 619th of 2000 higher than 1,382 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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