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NCT00891696 · ClinicalTrials.gov registry record · Phase 1
Nutritional and Contractile Regulation of Muscle Growth
A Phase 1 study, sponsored by The University of Texas Medical Branch, Galveston.
- Completed
- Registry status
- Phase 1
- Development phase
- 144
- Enrollment target
NCT00891696: Completed Phase 1 study, sponsored by The University of Texas Medical Branch, Galveston.
NCT00891696 is a Phase 1 study that has completed, run by The University of Texas Medical Branch, Galveston. The registered enrollment target is 144 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (140% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00891696, a Phase 1 study, has completed, sponsored by The University of Texas Medical Branch, Galveston.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 144 participants
- Enrollment target
Study Summary
Muscle wasting, which involves the loss of muscle tissue, is common in many conditions, such as cancer, AIDS, trauma, kidney failure, bone fracture, and sepsis. It is also prevalent among the elderly and in people who experience periods of physical inactivity and weightlessness. Muscle wasting can lead to overall weakness, immobility, physical dependence, and a greater risk of death when exposed to infection, surgery, or trauma. There is a need to develop scientifically based treatments that prevent muscle wasting. As one step towards such a goal, this study will examine the physiological and cellular mechanisms that regulate skeletal muscle growth.
Interventions
- DRUG Rapamycin
- OTHER Amino acid supplementation
- OTHER Low-intensity resistance exercise
- DRUG Sodium nitroprusside
- DEVICE Blood flow restriction cuff
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 144 participants |
| Start Date | 2009-04 |
| Est. Completion | 2015-03 |
| Phase | Phase 1 |
What the finished NCT00891696 record still lists
NCT00891696 is an interventional study that assigns participants to a tested intervention. The registered 144 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (140% higher).
The record links to 0 conditions, and to 5 interventions - of which Rapamycin is the first listed.
NCT00891696 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00891696 about?
NCT00891696 is a clinical study titled "Nutritional and Contractile Regulation of Muscle Growth". Muscle wasting, which involves the loss of muscle tissue, is common in many conditions, such as cancer, AIDS, trauma, kidney failure, bone fracture, and sepsis. It is also prevalent among the elderly and in people who experience periods of physical inactivity and weightlessness. Muscle wasting can l...
What is the current status of trial NCT00891696?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 144 participants. The study started on 2009-04. Estimated completion is 2015-03.
What interventions are being tested in trial NCT00891696?
The interventions under investigation include: Rapamycin (DRUG), Amino acid supplementation (OTHER), Low-intensity resistance exercise (OTHER), Sodium nitroprusside (DRUG), Blood flow restriction cuff (DEVICE).
Who is sponsoring clinical trial NCT00891696?
This trial is sponsored by The University of Texas Medical Branch, Galveston, which has 203 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00891696's enrollment target sits among peer trials
144 394th of 2000 higher than 1,600 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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