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NCT00882999 · ClinicalTrials.gov registry record · Phase 2

A Study of Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)

A Phase 2 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 2
Development phase
245
Enrollment target

NCT00882999: Completed Phase 2 study, sponsored by Eli Lilly and Company.

NCT00882999 is a Phase 2 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 245 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (84% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00882999, a Phase 2 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 2
Development phase
245 participants
Enrollment target

Study Summary

To look at the ability of LY2127399 to reduce magnetic resonance imaging (MRI) lesions at 12, 16, 20, and 24 weeks compared to placebo.

Primary Outcome

Lesions were measured using Gd-enhancing T1-weighted MRI scans. The number of T1-weighted lesions per scan was obtained from the number of T1-weighted lesions observed during a specified week divided by the number of scans performed that same week. To obtain the number of T1-weighted lesions per scan averaged during Weeks 12, 16, 20, and 24, the number of lesions per scan at each week was summed and then divided by the number of visits with non-missing lesion counts.

Interventions

  • DRUG Placebo
  • DRUG LY2127399

Trial Details

FieldValue
Enrollment Target 245 participants
Start Date 2009-04
Est. Completion 2012-06
Phase Phase 2
Eli Lilly and Company

1,341 total trials

What the finished NCT00882999 record still lists

NCT00882999 is an interventional study that assigns participants to a tested intervention. The registered 245 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (84% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00882999 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00882999 about?

NCT00882999 is a clinical study titled "A Study of Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)". To look at the ability of LY2127399 to reduce magnetic resonance imaging (MRI) lesions at 12, 16, 20, and 24 weeks compared to placebo.

What is the current status of trial NCT00882999?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 245 participants. The study started on 2009-04. Estimated completion is 2012-06.

What interventions are being tested in trial NCT00882999?

The interventions under investigation include: Placebo (DRUG), LY2127399 (DRUG).

Who is sponsoring clinical trial NCT00882999?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00882999's enrollment target sits among peer trials

245 234th of 2000 higher than 1,766 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00882999, the US trial registry maintained by the National Library of Medicine. NCT00882999 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.