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NCT00879918 · ClinicalTrials.gov registry record · Phase 1
Pharmacogenetics of Nicotine Metabolism in African-Americans
A Phase 1 study, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 1
- Development phase
- 70
- Enrollment target
NCT00879918: Completed Phase 1 study, sponsored by University of California, San Francisco.
NCT00879918 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 70 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00879918, a Phase 1 study, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 70 participants
- Enrollment target
Study Summary
The investigators hypothesize that African Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater intake of nicotine and tobacco smoke toxins), while whites smoke more for negative reinforcement with a "trough-maintaining" pattern (avoiding withdrawal by maintaining more consistent nicotine levels throughout the day by means of a more regular smoking pattern). The investigators believe that these patterns are linked to identifiable racial differences in nicotine pharmacology and that there will be associated racial differences in responses to pharmacologic interventions.
Interventions
- DRUG Deuterated nicotine and cotinine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2008-12 |
| Est. Completion | 2012-03 |
| Phase | Phase 1 |
What the finished NCT00879918 record still lists
NCT00879918 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher).
The record links to 0 conditions, and to 1 intervention - of which Deuterated nicotine and cotinine is the first listed.
NCT00879918 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00879918 about?
NCT00879918 is a clinical study titled "Pharmacogenetics of Nicotine Metabolism in African-Americans". The investigators hypothesize that African Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater intake of nicotine and tobacco smoke toxins), while whites smoke more for negative rein...
What is the current status of trial NCT00879918?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2008-12. Estimated completion is 2012-03.
What interventions are being tested in trial NCT00879918?
The interventions under investigation include: Deuterated nicotine and cotinine (DRUG).
Who is sponsoring clinical trial NCT00879918?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00879918's enrollment target sits among peer trials
70 749th of 2000 higher than 1,227 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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