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NCT00879918 · ClinicalTrials.gov registry record · Phase 1
Pharmacogenetics of Nicotine Metabolism in African-Americans
A Phase 1 study, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 1
- Development phase
- 70
- Enrollment target
NCT00879918 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 70 participants.
The verdict
NCT00879918, a Phase 1 study, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 70 participants
- Enrollment target
Study Summary
The investigators hypothesize that African Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater intake of nicotine and tobacco smoke toxins), while whites smoke more for negative reinforcement with a "trough-maintaining" pattern (avoiding withdrawal by maintaining more consistent nicotine levels throughout the day by means of a more regular smoking pattern). The investigators believe that these patterns are linked to identifiable racial differences in nicotine pharmacology and that there will be associated racial differences in responses to pharmacologic interventions.
Interventions
- DRUG Deuterated nicotine and cotinine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2008-12 |
| Est. Completion | 2012-03 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00879918
The ClinicalTrials.gov registry entry for NCT00879918 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Deuterated nicotine and cotinine is the first listed.
NCT00879918 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00879918 about?
NCT00879918 is a clinical study titled "Pharmacogenetics of Nicotine Metabolism in African-Americans". The investigators hypothesize that African Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater intake of nicotine and tobacco smoke toxins), while whites smoke more for negative rein...
What is the current status of trial NCT00879918?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2008-12. Estimated completion is 2012-03.
What interventions are being tested in trial NCT00879918?
The interventions under investigation include: Deuterated nicotine and cotinine (DRUG).
Who is sponsoring clinical trial NCT00879918?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
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