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NCT00879190 · ClinicalTrials.gov registry record · Phase 2

Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis

A Phase 2 study, sponsored by Stanford University.

Completed
Registry status
Phase 2
Development phase
92
Enrollment target

NCT00879190: Completed Phase 2 study, sponsored by Stanford University.

NCT00879190 is a Phase 2 study that has completed, run by Stanford University. The registered enrollment target is 92 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (31% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00879190, a Phase 2 study, has completed, sponsored by Stanford University.

COMPLETED
Registry status
Phase 2
Development phase
92 participants
Enrollment target

Study Summary

Chorioamnionitis is an infection of the placenta and amniotic membranes (bag of waters) surrounding the baby inside of a pregnant woman prior to delivery. This infection is somewhat common and is routinely treated with antibiotics given to the mother both before and after the baby is born. Currently it is not known what is the best choice of antibiotics to treat this type of infection, but commonly used treatments include Unasyn (ampicillin/sulbactam) or ampicillin/gentamicin. We plan to compare these two different antibiotic regimens to see if one is better than the other at treating and preventing bad outcomes from chorioamnionitis in women and babies.

Primary Outcome

Proportion of patients in each arm experiencing treatment success defined as resolution of fever by 24 hours postpartum

Interventions

  • DRUG Unasyn
  • DRUG Ampicillin/gentamicin

Trial Details

FieldValue
Enrollment Target 92 participants
Start Date 2009-05
Est. Completion 2012-06
Phase Phase 2
Stanford University

1,744 total trials

What the finished NCT00879190 record still lists

NCT00879190 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 92 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (31% lower).

The record links to 0 conditions, and to 2 interventions - of which Unasyn is the first listed.

NCT00879190 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00879190 about?

NCT00879190 is a clinical study titled "Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis". Chorioamnionitis is an infection of the placenta and amniotic membranes (bag of waters) surrounding the baby inside of a pregnant woman prior to delivery. This infection is somewhat common and is routinely treated with antibiotics given to the mother both before and after the baby is born. Currently...

What is the current status of trial NCT00879190?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 92 participants. The study started on 2009-05. Estimated completion is 2012-06.

What interventions are being tested in trial NCT00879190?

The interventions under investigation include: Unasyn (DRUG), Ampicillin/gentamicin (DRUG).

Who is sponsoring clinical trial NCT00879190?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00879190's enrollment target sits among peer trials

92 767th of 2000 higher than 1,230 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00879190, the US trial registry maintained by the National Library of Medicine. NCT00879190 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.