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NCT00878306 · ClinicalTrials.gov registry record · Phase 1

Disulfiram Interactions With HIV Medications: Clinical Implications

A Phase 1 study of HIV Infections and Drug Abuse, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target
1
Study location

NCT00878306 is a Phase 1 study of HIV Infections and Drug Abuse that has completed, run by University of California, San Francisco. The registered enrollment target is 40 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00878306, a Phase 1 study of HIV Infections and Drug Abuse, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine whether disulfiram might be a safe and effective treatment for cocaine and/or alcohol dependence in patients with HIV disease. This research is designed to characterize the presence or absence of significant drug interactions between disulfiram and HIV medications using standard clinical pharmacology techniques as well as monitor any side effects that might occur when these medications are administered together.

Interventions

  • DRUG Disulfiram
  • DRUG Disulfiram + Efavirenz
  • DRUG Disulfiram + Atazanavir
  • DRUG Disulfiram + Ritonavir

Study Locations (1)

California

  • San Francisco General Hospital - San Francisco

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2008-11
Est. Completion 2013-04
Phase Phase 1

What the Registry Record Tells You About NCT00878306

The ClinicalTrials.gov registry entry for NCT00878306 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (91% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 4 interventions - of which Disulfiram is the first listed.

NCT00878306 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT00878306 about?

NCT00878306 is a clinical study titled "Disulfiram Interactions With HIV Medications: Clinical Implications". The purpose of this study is to determine whether disulfiram might be a safe and effective treatment for cocaine and/or alcohol dependence in patients with HIV disease. This research is designed to characterize the presence or absence of significant drug interactions between disulfiram and HIV medic...

What is the current status of trial NCT00878306?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2008-11. Estimated completion is 2013-04.

What conditions does trial NCT00878306 study?

This clinical trial studies the following conditions: HIV Infections, Drug Abuse.

What interventions are being tested in trial NCT00878306?

The interventions under investigation include: Disulfiram (DRUG), Disulfiram + Efavirenz (DRUG), Disulfiram + Atazanavir (DRUG), Disulfiram + Ritonavir (DRUG).

Who is sponsoring clinical trial NCT00878306?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00878306 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.