Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00876798 · ClinicalTrials.gov registry record · Phase 3

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects With Euvolemic Hyponatremia

A Phase 3 study, sponsored by CardioKine.

Completed
Registry status
Phase 3
Development phase
206
Enrollment target

NCT00876798: Completed Phase 3 study, sponsored by CardioKine.

NCT00876798 is a Phase 3 study that has completed, run by CardioKine. The registered enrollment target is 206 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00876798, a Phase 3 study, has completed, sponsored by CardioKine.

COMPLETED
Registry status
Phase 3
Development phase
206 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and tolerability of oral lixivaptan capsules in subjects with Euvolemic Hyponatremia.

Interventions

  • DRUG Placebo
  • DRUG Lixivaptan

Trial Details

FieldValue
Enrollment Target 206 participants
Start Date 2009-06
Phase Phase 3
CardioKine

6 total trials

What the finished NCT00876798 record still lists

NCT00876798 is an interventional study that assigns participants to a tested intervention. The registered 206 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (73% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00876798 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00876798 about?

NCT00876798 is a clinical study titled "A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects With Euvolemic Hyponatremia". The purpose of this study is to evaluate the safety and tolerability of oral lixivaptan capsules in subjects with Euvolemic Hyponatremia.

What is the current status of trial NCT00876798?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 206 participants. The study started on 2009-06.

What interventions are being tested in trial NCT00876798?

The interventions under investigation include: Placebo (DRUG), Lixivaptan (DRUG).

Who is sponsoring clinical trial NCT00876798?

This trial is sponsored by CardioKine, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00876798's enrollment target sits among peer trials

206 1347th of 2000 higher than 651 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03373968 · 206 participants · Phase 2

    Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study

  • NCT03550391 · 206 participants · Phase 3

    Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

  • NCT04757116 · 206 participants · NA

    Post-Market Study to Assess iTind Safety in Comparison to UroLift

  • NCT05675865 · 206 participants · NA

    Cryoablation for Monomorphic Ventricular Tachycardia

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00876798, the US trial registry maintained by the National Library of Medicine. NCT00876798 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.