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NCT00874575 · ClinicalTrials.gov registry record · Phase 1

Nutritional Intervention for Age-related Muscular Function and Strength Losses

A Phase 1 study, sponsored by Metabolic Technologies.

Completed
Registry status
Phase 1
Development phase
76
Enrollment target

NCT00874575 is a Phase 1 study that has completed, run by Metabolic Technologies. The registered enrollment target is 76 participants.

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The verdict

NCT00874575, a Phase 1 study, has completed, sponsored by Metabolic Technologies.

COMPLETED
Registry status
Phase 1
Development phase
76 participants
Enrollment target

Study Summary

The purpose of the study is to * Test the effect of a dietary supplement beta-hydroxy-beta-methylbutyrate (HMB) with and without Vitamin D to prevent and reverse the losses of muscular strength and functionality in older adults. The second aim of the study is to determine if HMB and Vitamin D improves markers of bone turnover in adults aged 60 plus years. HMB is a dietary supplement that comes from the amino acid leucine. HMB is found in foods and is made in your body after you eat protein (meat). Subjects will be randomized to one of four dietary supplement groups and will participate in a 3-day per week exercise program for 12 weeks. Each exercise day will be about 60 minutes long consisting of strength training exercises utilizing Theraband® stretch cords and jumping. Subjects will consume the dietary supplement 2 times per day for 12 weeks. Tests will consist of the following: * Measuring the strength of subjects' legs by using a Isokinetic Dynamometer * Measuring body composition * Measuring hand-grip strength using a hand-grip dynamometer * Measuring functional mobility, balance and agility by the time it takes for you to rise from a chair, walk around a cone 8 feet in front of the chair and return to the chair (Up-\&-Go Test * Filling out questionnaires and having blood drawn for biochemical measurements. Testing will be performed at the beginning and at 4, 8 and 12 weeks.

Interventions

  • DIETARY_SUPPLEMENT Placebo
  • DIETARY_SUPPLEMENT Vitamin D
  • DIETARY_SUPPLEMENT Beta-hydroxy-Beta-methylbutyrate
  • DRUG Beta-hydroxy-Beta-methylbutyrate and Vitamin D

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2008-11
Est. Completion 2013-07
Phase Phase 1

Sponsor

Metabolic Technologies

16 total trials

What the Registry Record Tells You About NCT00874575

The ClinicalTrials.gov registry entry for NCT00874575 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 76 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Metabolic Technologies, which has 16 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT00874575 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00874575 about?

NCT00874575 is a clinical study titled "Nutritional Intervention for Age-related Muscular Function and Strength Losses". The purpose of the study is to * Test the effect of a dietary supplement beta-hydroxy-beta-methylbutyrate (HMB) with and without Vitamin D to prevent and reverse the losses of muscular strength and functionality in older adults. The second aim of the study is to determine if HMB and Vitamin D impr...

What is the current status of trial NCT00874575?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 76 participants. The study started on 2008-11. Estimated completion is 2013-07.

What interventions are being tested in trial NCT00874575?

The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Vitamin D (DIETARY_SUPPLEMENT), Beta-hydroxy-Beta-methylbutyrate (DIETARY_SUPPLEMENT), Beta-hydroxy-Beta-methylbutyrate and Vitamin D (DRUG).

Who is sponsoring clinical trial NCT00874575?

This trial is sponsored by Metabolic Technologies, which has 16 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.