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NCT00863551 · ClinicalTrials.gov registry record · Phase 4

Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART) Trial

A Phase 4 study, sponsored by Allergan.

Completed
Registry status
Phase 4
Development phase
12
Enrollment target

NCT00863551 is a Phase 4 study that has completed, run by Allergan. The registered enrollment target is 12 participants.

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The verdict

NCT00863551, a Phase 4 study, has completed, sponsored by Allergan.

COMPLETED
Registry status
Phase 4
Development phase
12 participants
Enrollment target

Study Summary

This study evaluates the penetration through the blood-brain-barrier of trospium chloride at plasma steady state (Day 10) in elderly subjects with overactive bladder symptoms. Trospium levels in cerebrospinal fluid (CSF) and peak and trough plasma levels will be measured. Baseline and day 10 post-dose neurocognitive testing will be compared using a reliable change index to assess if any study subject shows evidence of a clinically and statistically significant change in memory.

Interventions

  • DRUG Trospium Chloride

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2009-04
Est. Completion 2009-08
Phase Phase 4

Sponsor

Allergan

314 total trials

What the Registry Record Tells You About NCT00863551

The ClinicalTrials.gov registry entry for NCT00863551 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Allergan, which has 314 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Trospium Chloride is the first listed.

NCT00863551 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00863551 about?

NCT00863551 is a clinical study titled "Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART) Trial". This study evaluates the penetration through the blood-brain-barrier of trospium chloride at plasma steady state (Day 10) in elderly subjects with overactive bladder symptoms. Trospium levels in cerebrospinal fluid (CSF) and peak and trough plasma levels will be measured. Baseline and day 10 post-do...

What is the current status of trial NCT00863551?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 12 participants. The study started on 2009-04. Estimated completion is 2009-08.

What interventions are being tested in trial NCT00863551?

The interventions under investigation include: Trospium Chloride (DRUG).

Who is sponsoring clinical trial NCT00863551?

This trial is sponsored by Allergan, which has 314 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.