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NCT00859950 · ClinicalTrials.gov registry record · NA
Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea
A NA study, sponsored by Weill Medical College of Cornell University.
- Completed
- Registry status
- NA
- Development phase
- 70
- Enrollment target
NCT00859950: Completed NA study, sponsored by Weill Medical College of Cornell University.
NCT00859950 is a NA study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 70 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00859950, a NA study, has completed, sponsored by Weill Medical College of Cornell University.
- COMPLETED
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
Study Summary
Sleep apnea is a common sleep disorder characterized by temporary stops in breathing during sleep and has been associated with the development of cardiovascular disease. This research will investigate one potential mechanism leading to the development of cardiovascular disorder, specifically, the blockage of blood vessels called "vascular occlusion", in subjects with sleep apnea. A group of healthy controls will be used for comparison. All subjects will undergo clinical evaluation followed by an overnight sleep study and a morning blood draw. Subjects with sleep apnea will be treated according to standard clinical management and followed under the research protocol for one month. At the end of one month, a repeat blood draw will be performed on the sleep apnea subjects for comparative analysis. If a control subject is found to have any abnormality during this research study, he or she will be referred for further clinical evaluation.
Primary Outcome
The oxygen desaturation index (ODI) is the number of times per hour of sleep that the blood's oxygen level drop by a certain degree from baseline.
Interventions
- DEVICE Continuous Positive Airway Pressure (CPAP)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2009-04 |
| Est. Completion | 2015-08 |
| Phase | NA |
What the finished NCT00859950 record still lists
NCT00859950 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Continuous Positive Airway Pressure (CPAP) is the first listed.
NCT00859950 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00859950 about?
NCT00859950 is a clinical study titled "Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea". Sleep apnea is a common sleep disorder characterized by temporary stops in breathing during sleep and has been associated with the development of cardiovascular disease. This research will investigate one potential mechanism leading to the development of cardiovascular disorder, specifically, the bl...
What is the current status of trial NCT00859950?
This trial is currently completed. It is a NA study. The enrollment target is 70 participants. The study started on 2009-04. Estimated completion is 2015-08.
What interventions are being tested in trial NCT00859950?
The interventions under investigation include: Continuous Positive Airway Pressure (CPAP) (DEVICE).
Who is sponsoring clinical trial NCT00859950?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00859950's enrollment target sits among peer trials
70 1103rd of 2000 higher than 868 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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