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NCT00859937 · ClinicalTrials.gov registry record · Phase 2

Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors

A Phase 2 study of Recurrent Salivary Gland Carcinoma and Malignant Salivary Gland Neoplasm, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
55
Enrollment target
20
Study locations

NCT00859937 is a Phase 2 study of Recurrent Salivary Gland Carcinoma and Malignant Salivary Gland Neoplasm that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 55 participants, below the 124-participant average among 5 other Recurrent Salivary Gland Carcinoma trials with a reported enrollment target (56% lower). The trial reports 20 study locations across 8 states.

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The verdict

NCT00859937, a Phase 2 study of Recurrent Salivary Gland Carcinoma and Malignant Salivary Gland Neoplasm, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
55 participants
Enrollment target
20
Study locations

Study Summary

This phase II trial is studying how well dasatinib works in treating patients with malignant salivary gland tumors that have come back after treatment or have spread to other parts of the body. Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Dasatinib

Study Locations (20)

Illinois

  • University of Chicago Comprehensive Cancer Center - Chicago
  • Decatur Memorial Hospital - Decatur
  • NorthShore University HealthSystem-Evanston Hospital - Evanston
  • Ingalls Memorial Hospital - Harvey
  • Joliet Oncology-Hematology Associates Limited - Joliet
  • Loyola University Medical Center - Maywood
  • Illinois CancerCare-Peoria - Peoria
  • Central Illinois Hematology Oncology Center - Springfield

California

  • Tower Cancer Research Foundation - Beverly Hills
  • City of Hope Comprehensive Cancer Center - Duarte
  • USC / Norris Comprehensive Cancer Center - Los Angeles
  • Mercy UC Davis Cancer Center - Merced

Indiana

  • Fort Wayne Medical Oncology and Hematology Inc-Parkview - Fort Wayne
  • Northern Indiana Cancer Research Consortium - South Bend

Michigan

  • University of Michigan Comprehensive Cancer Center - Ann Arbor
  • Oncology Care Associates PLLC - Saint Joseph

Florida

  • Moffitt Cancer Center - Tampa

Georgia

  • Emory University Hospital/Winship Cancer Institute - Atlanta

Maryland

  • University of Maryland/Greenebaum Cancer Center - Baltimore

Missouri

  • Mercy Hospital Saint Louis - St Louis

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2009-03-16
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00859937

The ClinicalTrials.gov registry entry for NCT00859937 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 124-participant average among 5 other Recurrent Salivary Gland Carcinoma trials with a reported enrollment target (56% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Recurrent Salivary Gland Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT00859937 reports 20 study locations spanning 8 distinct geographic areas - top geographies include Illinois, California, Indiana.

Frequently Asked Questions

What is clinical trial NCT00859937 about?

NCT00859937 is a clinical study titled "Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors". This phase II trial is studying how well dasatinib works in treating patients with malignant salivary gland tumors that have come back after treatment or have spread to other parts of the body. Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

What is the current status of trial NCT00859937?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 2009-03-16.

What conditions does trial NCT00859937 study?

This clinical trial studies the following conditions: Recurrent Salivary Gland Carcinoma, Malignant Salivary Gland Neoplasm, Salivary Gland Adenoid Cystic Carcinoma, Stage IV Major Salivary Gland Cancer AJCC v7.

What interventions are being tested in trial NCT00859937?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Dasatinib (DRUG).

Who is sponsoring clinical trial NCT00859937?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00859937 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.