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Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors
NCT00859937 · View on ClinicalTrials.gov ↗
Study Summary
This phase II trial is studying how well dasatinib works in treating patients with malignant salivary gland tumors that have come back after treatment or have spread to other parts of the body. Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Conditions Studied
Interventions
- OTHER Laboratory Biomarker Analysis
- DRUG Dasatinib
Study Locations (20)
Illinois
- University of Chicago Comprehensive Cancer Center — Chicago
- Decatur Memorial Hospital — Decatur
- NorthShore University HealthSystem-Evanston Hospital — Evanston
- Ingalls Memorial Hospital — Harvey
- Joliet Oncology-Hematology Associates Limited — Joliet
- Loyola University Medical Center — Maywood
- Illinois CancerCare-Peoria — Peoria
- Central Illinois Hematology Oncology Center — Springfield
California
- Tower Cancer Research Foundation — Beverly Hills
- City of Hope Comprehensive Cancer Center — Duarte
- USC / Norris Comprehensive Cancer Center — Los Angeles
- Mercy UC Davis Cancer Center — Merced
Indiana
- Fort Wayne Medical Oncology and Hematology Inc-Parkview — Fort Wayne
- Northern Indiana Cancer Research Consortium — South Bend
Michigan
- University of Michigan Comprehensive Cancer Center — Ann Arbor
- Oncology Care Associates PLLC — Saint Joseph
Florida
- Moffitt Cancer Center — Tampa
Georgia
- Emory University Hospital/Winship Cancer Institute — Atlanta
Maryland
- University of Maryland/Greenebaum Cancer Center — Baltimore
Missouri
- Mercy Hospital Saint Louis — St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2009-03-16 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00859937
The ClinicalTrials.gov registry entry for NCT00859937 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 2,390 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with Recurrent Salivary Gland Carcinoma appearing as the primary indexed condition, and to 2 interventions — of which Laboratory Biomarker Analysis is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00859937 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Illinois, California, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00859937 about?
NCT00859937 is a clinical study titled "Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors". This phase II trial is studying how well dasatinib works in treating patients with malignant salivary gland tumors that have come back after treatment or have spread to other parts of the body. Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
What is the current status of trial NCT00859937?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 2009-03-16.
What conditions does trial NCT00859937 study?
This clinical trial studies the following conditions: Recurrent Salivary Gland Carcinoma, Malignant Salivary Gland Neoplasm, Salivary Gland Adenoid Cystic Carcinoma, Stage IV Major Salivary Gland Cancer AJCC v7. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00859937?
The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Dasatinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00859937?
This trial is sponsored by National Cancer Institute (NCI), which has 2,390 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00859937 being conducted?
This trial has 20 study locations across California, Florida, Georgia, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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