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NCT00849693 · ClinicalTrials.gov registry record · Phase 3
A Study in the Treatment of Children and Adolescents With Major Depressive Disorder
A Phase 3 study, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 3
- Development phase
- 463
- Enrollment target
NCT00849693: Completed Phase 3 study, sponsored by Eli Lilly and Company.
NCT00849693 is a Phase 3 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 463 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00849693, a Phase 3 study, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 463 participants
- Enrollment target
Study Summary
The purpose of this study is to assess whether duloxetine is superior to placebo in the treatment of children and adolescents with major depressive disorder (MDD)
Primary Outcome
CDRS-R Total score measure the presence and severity of depression in children. The scale consists of 17 items scored on a 1-to-5- or 1-to-7-point scale. A rating of 1 indicates normal functioning. Total scores range from 17 to 113. In general, scores below 20 indicate an absence of depression, scores of 20 to 30 indicate borderline depression, and scores of 40 to 60 indicate moderate depression. Least Square (LS) means are adjusted for baseline, pooled investigator, age category, visit, treatme
Interventions
- DRUG Placebo
- DRUG duloxetine
- DRUG fluoxetine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 463 participants |
| Start Date | 2009-03 |
| Est. Completion | 2011-09 |
| Phase | Phase 3 |
What the finished NCT00849693 record still lists
NCT00849693 is an interventional study that assigns participants to a tested intervention. The registered 463 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT00849693 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00849693 about?
NCT00849693 is a clinical study titled "A Study in the Treatment of Children and Adolescents With Major Depressive Disorder". The purpose of this study is to assess whether duloxetine is superior to placebo in the treatment of children and adolescents with major depressive disorder (MDD)
What is the current status of trial NCT00849693?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 463 participants. The study started on 2009-03. Estimated completion is 2011-09.
What interventions are being tested in trial NCT00849693?
The interventions under investigation include: Placebo (DRUG), duloxetine (DRUG), fluoxetine (DRUG).
Who is sponsoring clinical trial NCT00849693?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00849693's enrollment target sits among peer trials
463 821st of 2000 higher than 1,180 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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