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NCT00846729 · ClinicalTrials.gov registry record
Comparative Renal Function of Young (18-45 Years) and Ageing (55 Years and Above) Kidney Donors
A clinical trial, sponsored by Stanford University.
- Completed
- Registry status
- 120
- Enrollment target
NCT00846729: Completed study, sponsored by Stanford University.
NCT00846729 is a clinical trial that has completed, run by Stanford University. The registered enrollment target is 120 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00846729 has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- 120 participants
- Enrollment target
Study Summary
It is our purpose in this study to compare the kidney structure and function of older patients to that of young patients before and after removal of a single kidney for transplant donation and to examine the remaining kidney's ability to adapt and maintain function over time. More specifically, we aim to examine the effect of uninephrectomy on adaptive hyperfiltration in the remaining kidney. A secondary aim is to investigate whether subjects in the aging population undergo compensation to the same extent as younger subjects. We will also examine the compensatory rise in GFR (glomerular filtration rate) that follows uninephrectomy in both groups, and, again, compare the results in the aged versus young subjects. This will help in delineating the extent to which the aging population can be a potential source of living kidney donors for kidney transplantation. It is also our purpose with this study to refine the tests to be used in the donor evaluation process so as to accurately identify ideal candidates for safe kidney donation.
Interventions
- PROCEDURE CT angiogram of the remaining kidney.
- PROCEDURE Kidney Function study using Iothalamate & PAH as clearance markers
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2003-03 |
| Est. Completion | 2012-12 |
What the finished NCT00846729 record still lists
NCT00846729 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 2 interventions - of which CT angiogram of the remaining kidney. is the first listed.
NCT00846729 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00846729 about?
NCT00846729 is a clinical study titled "Comparative Renal Function of Young (18-45 Years) and Ageing (55 Years and Above) Kidney Donors". It is our purpose in this study to compare the kidney structure and function of older patients to that of young patients before and after removal of a single kidney for transplant donation and to examine the remaining kidney's ability to adapt and maintain function over time. More specifically, we a...
What is the current status of trial NCT00846729?
This trial is currently completed. The enrollment target is 120 participants. The study started on 2003-03. Estimated completion is 2012-12.
What interventions are being tested in trial NCT00846729?
The interventions under investigation include: CT angiogram of the remaining kidney. (PROCEDURE), Kidney Function study using Iothalamate & PAH as clearance markers (PROCEDURE).
Who is sponsoring clinical trial NCT00846729?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
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