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NCT00846521 · ClinicalTrials.gov registry record · Phase 4
Study of Post-meal Blood Sugar Peaks in Association With Vascular Disease in Childhood Obesity
A Phase 4 study, sponsored by Yale University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 23
- Enrollment target
NCT00846521 is a Phase 4 study that was terminated before completion, run by Yale University. The registered enrollment target is 23 participants.
The verdict
NCT00846521, a Phase 4 study, was terminated before completion, sponsored by Yale University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 23 participants
- Enrollment target
Study Summary
The main purpose of this study is to determine whether treatment with acarbose attenuates post-prandial glycemic excursions in non-diabetic/pre-diabetic obese children as determined by continuous glucose monitoring systems (CGMS). To this effect the current pilot study involves a 6 week intervention with acarbose given to all subjects with either impaired glucose tolerance or an area under the curve of \>130 mg/dl during the screening oral glucose tolerance test. Three consecutive days of CGMS are then compared to before and during the intervention. The secondary objective addressed in this protocol is the collection of baseline measures of endothelial function in obese and lean children. Even though the duration of acarbose treatment may be too short to demonstrate a vascular effect, the pre and post intervention data would serve as preliminary data for anticipated future studies that assess the vascular effect of reduced post-prandial blood glucose levels.
Interventions
- DRUG Acarbose
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2006-09 |
| Est. Completion | 2008-09 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00846521
The ClinicalTrials.gov registry entry for NCT00846521 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Acarbose is the first listed.
NCT00846521 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00846521 about?
NCT00846521 is a clinical study titled "Study of Post-meal Blood Sugar Peaks in Association With Vascular Disease in Childhood Obesity". The main purpose of this study is to determine whether treatment with acarbose attenuates post-prandial glycemic excursions in non-diabetic/pre-diabetic obese children as determined by continuous glucose monitoring systems (CGMS). To this effect the current pilot study involves a 6 week intervention...
What is the current status of trial NCT00846521?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 23 participants. The study started on 2006-09. Estimated completion is 2008-09.
What interventions are being tested in trial NCT00846521?
The interventions under investigation include: Acarbose (DRUG).
Who is sponsoring clinical trial NCT00846521?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
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