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NCT00834652 · ClinicalTrials.gov registry record · Phase 4
Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and Overweight
A Phase 4 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 4
- Development phase
- 206
- Enrollment target
NCT00834652: Completed Phase 4 study, sponsored by Washington University School of Medicine.
NCT00834652 is a Phase 4 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 206 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00834652, a Phase 4 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 206 participants
- Enrollment target
Study Summary
This study will determine whether the drug metformin improves the effects of traditional antidepressant medications in people who are overweight.
Primary Outcome
Beck Depression Inventory-II (BDI) scores 0-63, minimum score =0, maximum score =63, Higher scores represent worse outcome. Baseline scores are compared to scores after treatment.
Interventions
- DRUG Metformin
- DRUG Sertraline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 206 participants |
| Start Date | 2007-09 |
| Est. Completion | 2013-05 |
| Phase | Phase 4 |
What the finished NCT00834652 record still lists
NCT00834652 is an interventional study that assigns participants to a tested intervention. The registered 206 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 2 interventions - of which Metformin is the first listed.
NCT00834652 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00834652 about?
NCT00834652 is a clinical study titled "Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and Overweight". This study will determine whether the drug metformin improves the effects of traditional antidepressant medications in people who are overweight.
What is the current status of trial NCT00834652?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 206 participants. The study started on 2007-09. Estimated completion is 2013-05.
What interventions are being tested in trial NCT00834652?
The interventions under investigation include: Metformin (DRUG), Sertraline (DRUG).
Who is sponsoring clinical trial NCT00834652?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00834652's enrollment target sits among peer trials
206 401st of 2000 higher than 1,599 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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