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NCT00833326 · ClinicalTrials.gov registry record · Phase 1
A Study of ARRY-334543 and Docetaxel in Patients With Advanced Cancer
A Phase 1 study, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 27
- Enrollment target
NCT00833326: Completed Phase 1 study, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.
NCT00833326 is a Phase 1 study that has completed, run by Array Biopharma, now a wholly owned subsidiary of Pfizer. The registered enrollment target is 27 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00833326, a Phase 1 study, has completed, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 27 participants
- Enrollment target
Study Summary
This is a Phase 1 study during which patients with advanced/metastatic solid tumors will receive investigational study drug ARRY-334543 and docetaxel (with prophylactic growth factor support). Patients will receive increasing doses of study drug in combination with docetaxel in order to achieve the highest dose of study drug possible that will not cause unacceptable side effects. Patients will be followed to see what side effects the combination causes and what effectiveness the combination has, if any, in treating the cancer. Approximately 30 patients from the US will be enrolled in this study.
Interventions
- DRUG ARRY-334543, EGFR/ErbB2 inhibitor; oral
- DRUG Docetaxel, mitotic inhibitor; intravenous
- DRUG Prophylactic growth factors; subcutaneous
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2009-01 |
| Est. Completion | 2010-07 |
| Phase | Phase 1 |
What the finished NCT00833326 record still lists
NCT00833326 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 3 interventions - of which ARRY-334543, EGFR/ErbB2 inhibitor; oral is the first listed.
NCT00833326 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00833326 about?
NCT00833326 is a clinical study titled "A Study of ARRY-334543 and Docetaxel in Patients With Advanced Cancer". This is a Phase 1 study during which patients with advanced/metastatic solid tumors will receive investigational study drug ARRY-334543 and docetaxel (with prophylactic growth factor support). Patients will receive increasing doses of study drug in combination with docetaxel in order to achieve the ...
What is the current status of trial NCT00833326?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2009-01. Estimated completion is 2010-07.
What interventions are being tested in trial NCT00833326?
The interventions under investigation include: ARRY-334543, EGFR/ErbB2 inhibitor; oral (DRUG), Docetaxel, mitotic inhibitor; intravenous (DRUG), Prophylactic growth factors; subcutaneous (DRUG).
Who is sponsoring clinical trial NCT00833326?
This trial is sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer, which has 21 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00833326's enrollment target sits among peer trials
27 1463rd of 2000 higher than 519 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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