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NCT00827775 · ClinicalTrials.gov registry record · Phase 4
Mechanisms and Treatment of Intradialytic Hypertension
A Phase 4 study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 55
- Enrollment target
NCT00827775 is a Phase 4 study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 55 participants.
The verdict
NCT00827775, a Phase 4 study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 55 participants
- Enrollment target
Study Summary
1. To determine in a cross sectional case-controlled cohort study of 50 hemodialysis patients if blood pressure elevations with hemodialysis are associated with decreased endothelial cell function (measured by brachial artery flow mediated dilation and endothelial progenitor cell number), both of which are novel mechanistic markers in the causal pathway for detrimental cardiovascular outcomes; and 2. To determine if lowering blood pressure with carvedilol in 25 ESRD subjects with blood pressure elevations with hemodialysis can improve endothelial cell dysfunction as a surrogate mechanistic marker for improving cardiovascular outcomes.
Interventions
- DRUG Carvedilol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2009-06 |
| Est. Completion | 2010-09 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00827775
The ClinicalTrials.gov registry entry for NCT00827775 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Carvedilol is the first listed.
NCT00827775 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00827775 about?
NCT00827775 is a clinical study titled "Mechanisms and Treatment of Intradialytic Hypertension". 1. To determine in a cross sectional case-controlled cohort study of 50 hemodialysis patients if blood pressure elevations with hemodialysis are associated with decreased endothelial cell function (measured by brachial artery flow mediated dilation and endothelial progenitor cell number), both of wh...
What is the current status of trial NCT00827775?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 55 participants. The study started on 2009-06. Estimated completion is 2010-09.
What interventions are being tested in trial NCT00827775?
The interventions under investigation include: Carvedilol (DRUG).
Who is sponsoring clinical trial NCT00827775?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
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