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NCT00814073 · ClinicalTrials.gov registry record · Phase 3

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis

A Phase 3 study of Indolent Systemic Mastocytosis, sponsored by AB Science.

Completed
Registry status
Phase 3
Development phase
135
Enrollment target
20
Study locations

NCT00814073 is a Phase 3 study of Indolent Systemic Mastocytosis that has completed, run by AB Science. The registered enrollment target is 135 participants, below the 302-participant average among 3 other Indolent Systemic Mastocytosis trials with a reported enrollment target (55% lower). The trial reports 20 study locations across 3 states.

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The verdict

NCT00814073, a Phase 3 study of Indolent Systemic Mastocytosis, has completed, sponsored by AB Science.

COMPLETED
Registry status
Phase 3
Development phase
135 participants
Enrollment target
20
Study locations

Study Summary

The objective of this study is to compare the safety and efficacy of masitinib (AB1010) to placebo in patients with mastocytosis with handicap.

Interventions

  • DRUG Placebo
  • OTHER Best Supportive Care
  • DRUG Masitinib

Study Locations (20)

Other

  • CHU d'Amiens - Amiens
  • Hôpital Avicenne - Bobigny
  • CHU de Brest - Brest
  • CHU de Caen - Caen
  • CHU Clermont Ferrand - Clermont-Ferrand
  • Hôpital Claude Huriez - Lille
  • CHU Dupuytren - Limoges
  • Hôpital Ambroise Paré - Marseille
  • Hôpital Nord - Marseille
  • Hôpital Central - Nancy
  • CHU Hôtel Dieu - Nantes
  • Hôpital l'Archet II - Nice
  • Hôpital Necker - Paris
  • Hôpital Tenon - Paris
  • CHU Lyon Sud - Pierre-Bénite
  • Centre Hospitalier Lyon Sud - Pierre-Bénite
  • CHU Milétrie - Poitiers
  • CHU Hôpital Sud - Rennes

California

  • UC Davis Health System , Department of Dermatology - Sacramento

Texas

  • MD Anderson Cancer Centre - Houston

Trial Details

FieldValue
Enrollment Target 135 participants
Start Date 2008-12
Est. Completion 2015-11
Phase Phase 3

Sponsor

AB Science

8 total trials

What the Registry Record Tells You About NCT00814073

The ClinicalTrials.gov registry entry for NCT00814073 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 135 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 302-participant average among 3 other Indolent Systemic Mastocytosis trials with a reported enrollment target (55% lower). The listed sponsor is AB Science, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Indolent Systemic Mastocytosis appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT00814073 reports 20 study locations spanning 3 distinct geographic areas - top geographies include Other, California, Texas.

Frequently Asked Questions

What is clinical trial NCT00814073 about?

NCT00814073 is a clinical study titled "Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis". The objective of this study is to compare the safety and efficacy of masitinib (AB1010) to placebo in patients with mastocytosis with handicap.

What is the current status of trial NCT00814073?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 135 participants. The study started on 2008-12. Estimated completion is 2015-11.

What conditions does trial NCT00814073 study?

This clinical trial studies the following conditions: Indolent Systemic Mastocytosis.

What interventions are being tested in trial NCT00814073?

The interventions under investigation include: Placebo (DRUG), Best Supportive Care (OTHER), Masitinib (DRUG).

Who is sponsoring clinical trial NCT00814073?

This trial is sponsored by AB Science, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00814073 being conducted?

This trial has 20 study locations across California, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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