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NCT00813423 · ClinicalTrials.gov registry record · Phase 1

Sunitinib Malate and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Chemotherapy

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
40
Enrollment target

NCT00813423: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00813423 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 40 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00813423, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and best dose of sunitinib malate when given together with hydroxychloroquine in treating patients with advanced solid tumors that have not responded to chemotherapy. Sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Hydroxychloroquine may help sunitinib malate work better in treating solid tumors. Giving sunitinib malate together with hydroxychloroquine may kill more tumor cells.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Hydroxychloroquine
  • OTHER Pharmacological Study
  • DRUG Sunitinib Malate

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2010-02-19
Est. Completion 2023-07-18
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00813423

The ClinicalTrials.gov registry entry for NCT00813423 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT00813423 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00813423 about?

NCT00813423 is a clinical study titled "Sunitinib Malate and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Chemotherapy". This phase I trial studies the side effects and best dose of sunitinib malate when given together with hydroxychloroquine in treating patients with advanced solid tumors that have not responded to chemotherapy. Sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes neede...

What is the current status of trial NCT00813423?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2010-02-19. Estimated completion is 2023-07-18.

What interventions are being tested in trial NCT00813423?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Hydroxychloroquine (DRUG), Pharmacological Study (OTHER), Sunitinib Malate (DRUG).

Who is sponsoring clinical trial NCT00813423?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.