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NCT00812370 · ClinicalTrials.gov registry record · Phase 1
The UNBLOCK Study: Utilization of Bivalirudin On Clots in Kids
A Phase 1 study, sponsored by Children's Hospital Los Angeles.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT00812370: Completed Phase 1 study, sponsored by Children's Hospital Los Angeles.
NCT00812370 is a Phase 1 study that has completed, run by Children's Hospital Los Angeles. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00812370, a Phase 1 study, has completed, sponsored by Children's Hospital Los Angeles.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
Thrombosis is a significant medical complication in children with chronic diseases. The currently utilized treatments have many drawbacks which can lead to poor outcomes. More modern therapies are available but have not been systematically tested in children. This study will determine whether one such medication, bivalirudin is a safer and more effective alterative. This study will monitor what effects the drug has upon the child's body and how the body processes the study drug (absorption, metabolism and elimination). The study will also evaluate the drug's effectiveness by following how long it takes to dissolve the clot. The safety issues being monitored relate to any observations of major or minor bleeding episodes after taking the drug, and/or any other side effects.
Interventions
- DRUG Bivalirudin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2008-09 |
| Est. Completion | 2013-07 |
| Phase | Phase 1 |
What the finished NCT00812370 record still lists
NCT00812370 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 1 intervention - of which Bivalirudin is the first listed.
NCT00812370 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00812370 about?
NCT00812370 is a clinical study titled "The UNBLOCK Study: Utilization of Bivalirudin On Clots in Kids". Thrombosis is a significant medical complication in children with chronic diseases. The currently utilized treatments have many drawbacks which can lead to poor outcomes. More modern therapies are available but have not been systematically tested in children. This study will determine whether one su...
What is the current status of trial NCT00812370?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2008-09. Estimated completion is 2013-07.
What interventions are being tested in trial NCT00812370?
The interventions under investigation include: Bivalirudin (DRUG).
Who is sponsoring clinical trial NCT00812370?
This trial is sponsored by Children's Hospital Los Angeles, which has 119 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00812370's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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