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NCT00809094 · ClinicalTrials.gov registry record · Phase 2

NAC Phase IIB: A Multi-Center, Phase IIB, Randomized, Placebo-controlled, Double-Blind Study Of The Effects Of N-Acetylcysteine On Redox Changes and Lung Inflammation In Cystic Fibrosis Patients

A Phase 2 study, sponsored by Stanford University.

Completed
Registry status
Phase 2
Development phase
70
Enrollment target

NCT00809094: Completed Phase 2 study, sponsored by Stanford University.

NCT00809094 is a Phase 2 study that has completed, run by Stanford University. The registered enrollment target is 70 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00809094, a Phase 2 study, has completed, sponsored by Stanford University.

COMPLETED
Registry status
Phase 2
Development phase
70 participants
Enrollment target

Study Summary

This Phase IIB proof-of-concept study would examine the effects of an investigational product called N-acetylcysteine (NAC) on the basic processes that cause inflammation in CF lung disease. We hope to learn more about the causes of lung disease in cystic fibrosis by studying the characteristics of the inflammation in the lungs of patients who have CF.

Primary Outcome

(change in log10 HNE in the active treatment group) - (change in log10 HNE in the placebo group)

Interventions

  • DRUG Placebo
  • DRUG N-acetylcysteine (NAC)

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2008-11
Est. Completion 2011-02
Phase Phase 2
Stanford University

1,744 total trials

What the finished NCT00809094 record still lists

NCT00809094 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (47% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00809094 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00809094 about?

NCT00809094 is a clinical study titled "NAC Phase IIB: A Multi-Center, Phase IIB, Randomized, Placebo-controlled, Double-Blind Study Of The Effects Of N-Acetylcysteine On Redox Changes and Lung Inflammation In Cystic Fibrosis Patients". This Phase IIB proof-of-concept study would examine the effects of an investigational product called N-acetylcysteine (NAC) on the basic processes that cause inflammation in CF lung disease. We hope to learn more about the causes of lung disease in cystic fibrosis by studying the characteristics of ...

What is the current status of trial NCT00809094?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2008-11. Estimated completion is 2011-02.

What interventions are being tested in trial NCT00809094?

The interventions under investigation include: Placebo (DRUG), N-acetylcysteine (NAC) (DRUG).

Who is sponsoring clinical trial NCT00809094?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00809094's enrollment target sits among peer trials

70 937th of 2000 higher than 1,036 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00809094, the US trial registry maintained by the National Library of Medicine. NCT00809094 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.