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NCT00799240 · ClinicalTrials.gov registry record · Phase 2

MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer

A Phase 2 study, sponsored by University of Kansas.

Completed
Registry status
Phase 2
Development phase
27
Enrollment target

NCT00799240: Completed Phase 2 study, sponsored by University of Kansas.

NCT00799240 is a Phase 2 study that has completed, run by University of Kansas. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00799240, a Phase 2 study, has completed, sponsored by University of Kansas.

COMPLETED
Registry status
Phase 2
Development phase
27 participants
Enrollment target

Study Summary

This study will compare the rate of chemotherapy: pemetrexed and cisplatin compared with the combination of pemetrexed/cisplatin with MK-0646. The other purposes are to determine how long we can control the cancer growth and toxicity and safety of the combination. Laboratory research with the tumor tissue and blood obtained will be done to assess IGF-1R expression and related markers and correlate with response and survival.

Interventions

  • DRUG Arm A: Pemetrexed Cisplatin
  • DRUG Arm B Pemetrexed, Cisplatin and MK-0646

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2009-06
Est. Completion 2014-07
Phase Phase 2
University of Kansas

66 total trials

What the finished NCT00799240 record still lists

NCT00799240 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 2 interventions - of which Arm A: Pemetrexed Cisplatin is the first listed.

NCT00799240 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00799240 about?

NCT00799240 is a clinical study titled "MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung Cancer". This study will compare the rate of chemotherapy: pemetrexed and cisplatin compared with the combination of pemetrexed/cisplatin with MK-0646. The other purposes are to determine how long we can control the cancer growth and toxicity and safety of the combination. Laboratory research with the tumor ...

What is the current status of trial NCT00799240?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2009-06. Estimated completion is 2014-07.

What interventions are being tested in trial NCT00799240?

The interventions under investigation include: Arm A: Pemetrexed Cisplatin (DRUG), Arm B Pemetrexed, Cisplatin and MK-0646 (DRUG).

Who is sponsoring clinical trial NCT00799240?

This trial is sponsored by University of Kansas, which has 66 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00799240's enrollment target sits among peer trials

27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00799240, the US trial registry maintained by the National Library of Medicine. NCT00799240 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.