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NCT00788541 · ClinicalTrials.gov registry record · Phase 2

A Dose-Volume Study of a Treatment for Elevated IOP Due to Open-Angle Glaucoma or Ocular Hypertension

A Phase 2 study, sponsored by Alcon Research.

Terminated
Registry status
Phase 2
Development phase
197
Enrollment target

NCT00788541: Clinical Trial Phase 2 study, sponsored by Alcon Research.

NCT00788541 is a Phase 2 study that was terminated before completion, run by Alcon Research. The registered enrollment target is 197 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (48% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00788541, a Phase 2 study, was terminated before completion, sponsored by Alcon Research.

TERMINATED
Registry status
Phase 2
Development phase
197 participants
Enrollment target

Study Summary

The purpose of this study was to assess the effects of total volume and total dose on the safety and intraocular pressure-lowering efficacy of Anecortave Acetate Suspension (3 mg and 48 mg) in 0.5 mL and 0.8 mL volumes when administered by anterior juxtascleral depot (AJD) for the treatment of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Interventions

  • OTHER Anecortave Acetate Vehicle
  • DRUG Anecortave Acetate Sterile Suspension, 6 mg/mL
  • DRUG Anecortave Acetate Sterile Suspension, 3.75 mg/mL
  • DRUG Anecortave Acetate Sterile Suspension, 96 mg/mL
  • DRUG Anecortave Acetate Sterile Suspension, 60 mg/ML

Trial Details

FieldValue
Enrollment Target 197 participants
Start Date 2008-12
Est. Completion 2009-09
Phase Phase 2
Alcon Research

275 total trials

Why NCT00788541 stopped before completion

NCT00788541 is an interventional study that assigns participants to a tested intervention. The registered 197 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (48% higher).

The record links to 0 conditions, and to 5 interventions - of which Anecortave Acetate Vehicle is the first listed.

NCT00788541 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00788541 about?

NCT00788541 is a clinical study titled "A Dose-Volume Study of a Treatment for Elevated IOP Due to Open-Angle Glaucoma or Ocular Hypertension". The purpose of this study was to assess the effects of total volume and total dose on the safety and intraocular pressure-lowering efficacy of Anecortave Acetate Suspension (3 mg and 48 mg) in 0.5 mL and 0.8 mL volumes when administered by anterior juxtascleral depot (AJD) for the treatment of eleva...

What is the current status of trial NCT00788541?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 197 participants. The study started on 2008-12. Estimated completion is 2009-09.

What interventions are being tested in trial NCT00788541?

The interventions under investigation include: Anecortave Acetate Vehicle (OTHER), Anecortave Acetate Sterile Suspension, 6 mg/mL (DRUG), Anecortave Acetate Sterile Suspension, 3.75 mg/mL (DRUG), Anecortave Acetate Sterile Suspension, 96 mg/mL (DRUG), Anecortave Acetate Sterile Suspension, 60 mg/ML (DRUG).

Who is sponsoring clinical trial NCT00788541?

This trial is sponsored by Alcon Research, which has 275 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00788541's enrollment target sits among peer trials

197 349th of 2000 higher than 1,652 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00788541, the US trial registry maintained by the National Library of Medicine. NCT00788541 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.