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NCT00785928 · ClinicalTrials.gov registry record · Phase 2
A Study for Patients With Active Rheumatoid Arthritis Despite Ongoing Methotrexate Therapy
A Phase 2 study, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 2
- Development phase
- 158
- Enrollment target
NCT00785928: Completed Phase 2 study, sponsored by Eli Lilly and Company.
NCT00785928 is a Phase 2 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 158 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (19% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00785928, a Phase 2 study, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 158 participants
- Enrollment target
Study Summary
To assess the efficacy of LY2127399 versus placebo using American College of Rheumatology (ACR)50 response scale at 24 weeks
Primary Outcome
ACR50 Responder Index is a composite of clinical, laboratory, and functional measures in rheumatoid arthritis. An ACR50 Responder is defined as a participant with \>50% improvement from baseline in both tender and swollen joint counts and in at least 3 of the following 5 criteria: physician global assessment, participant global assessment, functional ability measure (Health Assessment Questionnaire-Disability Index which measures participants' perceived degree of difficulty when performing vario
Interventions
- DRUG Placebo
- BIOLOGICAL LY2127399
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 158 participants |
| Start Date | 2008-10 |
| Est. Completion | 2010-12 |
| Phase | Phase 2 |
What the finished NCT00785928 record still lists
NCT00785928 is an interventional study that assigns participants to a tested intervention. The registered 158 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (19% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00785928 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00785928 about?
NCT00785928 is a clinical study titled "A Study for Patients With Active Rheumatoid Arthritis Despite Ongoing Methotrexate Therapy". To assess the efficacy of LY2127399 versus placebo using American College of Rheumatology (ACR)50 response scale at 24 weeks
What is the current status of trial NCT00785928?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 158 participants. The study started on 2008-10. Estimated completion is 2010-12.
What interventions are being tested in trial NCT00785928?
The interventions under investigation include: Placebo (DRUG), LY2127399 (BIOLOGICAL).
Who is sponsoring clinical trial NCT00785928?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00785928's enrollment target sits among peer trials
158 443rd of 2000 higher than 1,558 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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