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NCT00774397 · ClinicalTrials.gov registry record · Phase 2

Antiviral Effect, Safety, and Pharmacokinetics of BI201335 +PegIFN/RBV in HCV-GT1 (SILEN-C1&2)

A Phase 2 study, sponsored by Boehringer Ingelheim.

Completed
Registry status
Phase 2
Development phase
719
Enrollment target

NCT00774397 is a Phase 2 study that has completed, run by Boehringer Ingelheim. The registered enrollment target is 719 participants.

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The verdict

NCT00774397, a Phase 2 study, has completed, sponsored by Boehringer Ingelheim.

COMPLETED
Registry status
Phase 2
Development phase
719 participants
Enrollment target

Study Summary

The objective was to investigate the antiviral effect, safety, and pharmacokinetics of BI 201335 (Faldaprevir), given as a soft gelatine capsule, in patients with hepatitis C virus (HCV) genotype 1 infection. Combination therapy of BI 201335 (Faldaprevir) with pegylated interferon α-2a (PegIFN) and ribavirin (RBV), with or without a 3-day lead-in, was assessed in treatment-naïve (TN) and treatment experienced (TE) patients.

Interventions

  • DRUG PegIFN/RBV
  • DRUG BI 201335 NA 240 mg QD / LI
  • DRUG BI 201335 NA 120mg QD / LI
  • DRUG BI 201335 NA 240 mg QD

Trial Details

FieldValue
Enrollment Target 719 participants
Start Date 2008-10
Phase Phase 2

Sponsor

Boehringer Ingelheim

515 total trials

What the Registry Record Tells You About NCT00774397

The ClinicalTrials.gov registry entry for NCT00774397 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 719 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boehringer Ingelheim, which has 515 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which PegIFN/RBV is the first listed.

NCT00774397 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00774397 about?

NCT00774397 is a clinical study titled "Antiviral Effect, Safety, and Pharmacokinetics of BI201335 +PegIFN/RBV in HCV-GT1 (SILEN-C1&2)". The objective was to investigate the antiviral effect, safety, and pharmacokinetics of BI 201335 (Faldaprevir), given as a soft gelatine capsule, in patients with hepatitis C virus (HCV) genotype 1 infection. Combination therapy of BI 201335 (Faldaprevir) with pegylated interferon α-2a (PegIFN) and ...

What is the current status of trial NCT00774397?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 719 participants. The study started on 2008-10.

What interventions are being tested in trial NCT00774397?

The interventions under investigation include: PegIFN/RBV (DRUG), BI 201335 NA 240 mg QD / LI (DRUG), BI 201335 NA 120mg QD / LI (DRUG), BI 201335 NA 240 mg QD (DRUG).

Who is sponsoring clinical trial NCT00774397?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.