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NCT00765752 · ClinicalTrials.gov registry record

Cortical GABA Concentrations in Insomnia

A clinical trial, sponsored by Yale University.

Completed
Registry status
23
Enrollment target

NCT00765752: Completed study, sponsored by Yale University.

NCT00765752 is a clinical trial that has completed, run by Yale University. The registered enrollment target is 23 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00765752 has completed, sponsored by Yale University.

COMPLETED
Registry status
23 participants
Enrollment target

Study Summary

Disturbances in the amino acid neurotransmitter (AANt), gamma-amino butyric acid (GABA) function are hypothesized to contribute to the neurobiology of Major Depressive Disorder (MDD) and insomnia. The principal objective of this project is to use magnetic resonance spectroscopy (MRS) to provide the first in vivo characterization of cortical GABA levels in individuals with primary insomnia, and to determine whether subjects with MDD, achieving a partial response with selective serotonin reuptake inhibitor treatment but still experiencing significant residual symptoms including insomnia, have altered levels of this neurotransmitter. The investigators are also exploring the correlation between cortical AANt levels and abnormalities in sleep parameters in primary insomnia and as a residual symptom of major depression.

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2007-11
Est. Completion 2011-06
Yale University

1,492 total trials

What the finished NCT00765752 record still lists

NCT00765752 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 23 participants, a relatively small participant target.

The record links to 0 conditions, and to 0 interventions.

NCT00765752 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00765752 about?

NCT00765752 is a clinical study titled "Cortical GABA Concentrations in Insomnia". Disturbances in the amino acid neurotransmitter (AANt), gamma-amino butyric acid (GABA) function are hypothesized to contribute to the neurobiology of Major Depressive Disorder (MDD) and insomnia. The principal objective of this project is to use magnetic resonance spectroscopy (MRS) to provide the ...

What is the current status of trial NCT00765752?

This trial is currently completed. The enrollment target is 23 participants. The study started on 2007-11. Estimated completion is 2011-06.

Who is sponsoring clinical trial NCT00765752?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT00765752, the US trial registry maintained by the National Library of Medicine. NCT00765752 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.